Improving Walking in Older Adults With Knee Osteoarthritis - Tabular View

Tracking Information

First Received Date ^ICMJE

December 20, 2007

Last Updated Date

February 13, 2009

Start Date ^ICMJE

December 2007

Estimated Primary Completion Date

September 2008 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Changes in functional limitation assessed by the A) Summary Performance Score which includes balance tests, timed 4-meter walk, and timed chair stand test B) Timed stair climb C) Late Life Function and Disability Instrument (LLFDI) Questionnaire [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
Changes in the disability measure, a timed 400 meter walk [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]
Changes in impairments assessed using the Knee and Osteoarthritis Outcome Score (KOOS) questionnaire [ Time Frame: 12 Weeks ] [ Designated as safety issue: No ]

Original Primary Outcome Measures ^ICMJE

Changes in functional limitation assessed by the A) Summary Performance Score which includes balance tests, timed 4-meter walk, and timed chair stand test B) Timed stair climb C) Late Life Function and Disability Instrument (LLFDI) Questionnaire [ Time Frame: 3 months ] [ Designated as safety issue: No ]
Changes in the disability measure, a timed 400 meter walk [ Time Frame: 3 months ] [ Designated as safety issue: No ]
Changes in impairments assessed using the Knee and Osteoarthritis Outcome Score (KOOS) questionnaire [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Change History

Complete list of historical versions of study NCT00583245 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Improving Walking in Older Adults With Knee Osteoarthritis

Official Title ^ICMJE

Optimizing Mobility in Older Adults With Knee Osteoarthritis

Brief Summary

Knee osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The long-term objective of this research is to reduce disablement of older adults with symptomatic knee OA. The principle of specificity of training indicates that exercises that closely approximate the goal functional activity are most effective in improving physical performance during that activity. Based on this principle, the specific aim of this pilot study is to design a patient-specific gait training intervention using analysis of compensatory joint moments and energy expenditure. Successful completion will inform rehabilitation for maintaining or improving mobility as well as explore the mechanism of effect.

Detailed Description

Study Phase

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study

Condition ^ICMJE

Knee Osteoarthritis

Intervention ^ICMJE

Other: Gait Training

Study Arms / Comparison Groups

Experimental: Gait training

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Active, not recruiting

Estimated Enrollment ^ICMJE

Estimated Completion Date

December 2009

Estimated Primary Completion Date

September 2008 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by x-ray and frequent knee symptoms)
Age 60 or older

Exclusion Criteria:

acute or terminal illness
unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring the use of supplemental oxygen, neurological disease that affects gait, or lower limb musculoskeletal surgery in the past 6 months.
Bilateral knee replacement

Gender

Both

Ages

60 Years and older

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

United States

Administrative Information

NCT ID ^ICMJE

NCT00583245

Responsible Party

Neil Segal, MD, The University of Iowa

Study ID Numbers ^ICMJE

NCT00331110, 1K23AG030945-01

Study Sponsor ^ICMJE

University of Iowa

Collaborators ^ICMJE

National Institute on Aging (NIA)

Investigators ^ICMJE

Principal Investigator:

Neil Segal, MD

University of Iowa

Information Provided By

University of Iowa

Verification Date

February 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP