Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2010 by Stanford University.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
TRDRP
Information provided by:
Stanford University
ClinicalTrials.gov Identifier:
NCT00568906
First received: December 4, 2007
Last updated: July 2, 2010
Last verified: July 2010

December 4, 2007
July 2, 2010
February 2002
November 2010   (final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT00568906 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma

This study will investigate gene expression profiles in normal human lung tissue, lung carcinoma and metastatic tumor to the lung. The expression of up to 20,000 genes in a given lung tissue sample will be examined by cDNA microarray analysis and compared to normal lung tissue. In addition, we hope to identify a particular subset of lung cancer cells with an enhanced capacity for proliferation and self-renewal , analogous to the stem cells recently identified for certain types of leukemia, breast cancer and brain tumors.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

Lung tissue or pleural fluid.

Non-Probability Sample

Patients who agree to participate in this study will be those who are undergoing wedge resection, lobectomy on pneumonectomy for clinically diagnosed lung carcinoma or metastatic tumors to the lung, or who are undergoing therapeutic or diagnostic thoracentesis for malignant pleural effusion.

  • Carcinoma, Giant Cell
  • Carcinoma, Non-Small-Cell Lung
  • Lung Cancer
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
150
June 2011
November 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:Adults with non small cell lung cancer

Exclusion Criteria:NA

Both
18 Years and older
No
Contact: Susan Jacobs, RN (650) 725-8082 ssjpulm@stanford.edu
United States
 
NCT00568906
SU-11062007-807, 76094, LUN0011
Not Provided
Glenn D. Rosen, Stanford University School of Medicine
Stanford University
TRDRP
Principal Investigator: Daya Upadhyay Stanford University
Principal Investigator: Glenn D. Rosen Stanford University
Stanford University
July 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP