Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT) (PET-CRT)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2012 by University Medical Centre Groningen.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
I.C. Van Gelder, University Medical Centre Groningen
ClinicalTrials.gov Identifier:
NCT00567645
First received: December 4, 2007
Last updated: June 18, 2012
Last verified: June 2012

December 4, 2007
June 18, 2012
July 2007
Not Provided
sympathetic innervation in patients with chronic heart failure (CHF) [ Time Frame: 6 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00567645 on ClinicalTrials.gov Archive Site
NYHA class Echocardiographic parameters: LVEDD, LVESD, LVEF, LVESV,IVMD, and septal to lateral delay Hospitalization for heart failure Maximal oxygen consumption NT pro-BNP changes [ Time Frame: 6 months ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT)
Identification of the Role of Sympathetic Innervation in Heart Failure Patients Treated With Cardiac Resynchronization Therapy. A Pilot Study

The purpose of this study is to assess whether baseline sympathetic innervation in patients with chronic heart failure (CHF) is predictive for response to cardiac resynchronization therapy (CRT). And to assess whether response to CRT coincides with restoration of regional sympathetic innervation.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Retrospective
Not Provided
Not Provided
Non-Probability Sample

chronic heart failure patients with CRT

  • Sympathetic Innervation
  • Chronic Heart Failure
Not Provided
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Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
15
December 2012
Not Provided

Inclusion Criteria:

  • Indication for CRT
  • Stable optimal medication
  • Non ischemic cardiomyopathy

Exclusion Criteria:

  • Age less then 18 years
  • Previous CRT
  • Clinically relevant valvular heart disease or coronary artery disease
  • Acute or chronic infection
  • Untreated clinical hypo- or hyperthyroidism or < 3 months euthyroidism
  • Uncontrolled hypertension, defined as a systolic blood pressure > 160 mm Hg and/or a diastolic blood pressure > 95 mm Hg
  • A concurrent medical condition (i.e. alcohol or drug abuse or a severe progressive extra cardiac disease or M. Parkinson) or is unlikely to comply with the protocol
  • Participation to a previous protocol involving radioactivity in the past year
  • Pregnancy
Both
18 Years to 85 Years
No
Contact: Isabelle C Van Gelder, Prof 050-3612355 i.c.van.gelder@thorax.umcg.nl
Netherlands
 
NCT00567645
16716
No
I.C. Van Gelder, University Medical Centre Groningen
University Medical Centre Groningen
Not Provided
Principal Investigator: Isabelle C. Van Gelder, Prof University Medical Center Groningen, departmen cardiology
University Medical Centre Groningen
June 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP