Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2007 by Rudolf Foundation Clinic.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Rudolf Foundation Clinic
ClinicalTrials.gov Identifier:
NCT00533754
First received: September 20, 2007
Last updated: NA
Last verified: September 2007
History: No changes posted

September 20, 2007
September 20, 2007
July 2006
Not Provided
higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals
Same as current
No Changes Posted
a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD
Same as current
Not Provided
Not Provided
 
Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population
Y402H Comlement Factor H Polymorphism and Age-Related Macular Degeneration in the Austrian Population

The aim of the study is to show a higher expression of the Y402H polymorphism in the complement factor H in patients with AMD compared to healthy individuals.

Additionaly a correlation between a subsided infection with chlamydia and patients with AMD and a factor H polymorphism will be investigated. An interrelationship with the VEGF-plasma level shall give more hints into the pathomechanism of AMD.

Not Provided
Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Basic Science
Age-Related Macular Degeneration
Procedure: drawing blood
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
Not Provided
November 2007
Not Provided

Inclusion Criteria:

  • man and women over 18 years old
  • Filled out informed consentBereitschaft zur Teilnahme
  • Diagnosis of non-exudative/ exudative age related macular dgeneneration

Exclusion Criteria:

  • inherited retinal diseases
  • other aquired retinal/ macular
  • missing informed consent
Both
55 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Austria
 
NCT00533754
EK 06-076-VK, EK 06-076-VK
No
Not Provided
Rudolf Foundation Clinic
Not Provided
Study Chair: Susanne Binder, M.D. Rudoulf Foundation Clinic
Rudolf Foundation Clinic
September 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP