Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infectionsin Adults

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT00524108
First received: August 31, 2007
Last updated: August 14, 2012
Last verified: August 2012

August 31, 2007
August 14, 2012
August 2007
December 2010   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT00524108 on ClinicalTrials.gov Archive Site
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Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infectionsin Adults
Retrospective Analysis of Clinical Features in Ventriculoperitoneal Shunt Infections and Time to Re-Implantation in Adults

The objectives of this study are:

  • To describe the incidence of clinical features in adults with internal ventriculoperitoneal (VP) shunt infections,
  • To determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and
  • To evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

Information from medical records of patients seen by the PI will be collected and analyzed to describe the incidence of clinical features in adults with internal ventriculoperitoneal shunt infections, to determine the validity of laboratory parameters in adults with internal ventriculoperitoneal shunt infections and to evaluate the relationship between the timing of shunt re-implantation with the rates of relapse and secondary infection.

Observational
Observational Model: Cohort
Time Perspective: Retrospective
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Probability Sample

VP shunt infection

  • Ventriculoperitoneal Shunt
  • Infection
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
350
December 2010
December 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Adults (age >= 18 yrs) with VP shunts (ventriculoatrial [VA], and other cerebrospinal fluid [CSF] catheters will not be included).
  • Cases will include patients with a diagnosis of VP shunt infection.
  • Controls will be patients with a clinical suspicion of shunt infections with negative CSF cultures.

Exclusion Criteria:

  • Patients with meningitis from community acquired organisms (e.g. Streptococcus pneumoniae, Neisseria meningitidis, Listeria monocytogenes and Haemophilus Influenzae).
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00524108
PRO07080212
Yes
University of Pittsburgh
University of Pittsburgh
Not Provided
Principal Investigator: Adarsh Bhimraj, MD University of Pittsburgh
University of Pittsburgh
August 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP