Correlation Between Access Blood Flow and Extracorporeal Blood Flow - Tabular View

Tracking Information

First Received Date ^ICMJE

August 28, 2007

Last Updated Date

March 17, 2009

Start Date ^ICMJE

March 2008

Estimated Primary Completion Date

June 2009 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Original Primary Outcome Measures ^ICMJE

Change History

Complete list of historical versions of study NCT00522704 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Correlation Between Access Blood Flow and Extracorporeal Blood Flow

Official Title ^ICMJE

Correlation Between Access Blood Flow and Extracorporeal Blood Flow

Brief Summary

The purpose of this study is to determine if Effective Extracorporeal Blood Flow(eEBF) has correlation with Access Blood Flow (Qa), when eEBF adjusts with Dynamic Arterial Line Pressure (DALP) in patients with Arteriovenous fistulae in hemodialysis treatment.

Detailed Description

Accesses that show a large (>15%) decrement over time in vascular access blood flow are associated with a high risk of thrombosis. Serial measurements of vascular access blood flow predict access thrombosis. At the moment, the measurement of access flow is time consuming, operator dependent, so that it cannot be done with every treatment. We hypothesized that extracorporeal blood flow at pressure of -200 to -260 mmHg in arterial line has correlation with access blood flow and this can be used to estimate access blood flow.

Study Phase

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Cohort, Prospective

Condition ^ICMJE

Arteriovenous Fistula

Intervention ^ICMJE

Other: Dynamic Arterial line Pressure (DALP)

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Recruiting

Estimated Enrollment ^ICMJE

Estimated Completion Date

August 2009

Estimated Primary Completion Date

June 2009 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Patients with Chronic Kidney Disease K-DIGO 5d in hemodialysis treatment)
Permanent vascular accesses with native arteriovenous fistulas (AVF)
AVF that were at least 12 weeks old

Exclusion Criteria:

Inflammation and pain in AVF
Negation to participate in the study

Gender

Both

Ages

18 Years to 80 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact: Franklin B Mora, M.D.	593 72 868084	franklin.mora.bravo@gmail.com
Contact: Luis R Mariscal, M.D.	52 55 55 7932911 ext 1262	mariscalmd@yahoo.com.mx

Location Countries ^ICMJE

Mexico

Administrative Information

NCT ID ^ICMJE

NCT00522704

Responsible Party

Correlation between access blood flow and effective extracorporeal blood flow, Instituto Nacional de Cardiologia Ignacio Chavez

Study ID Numbers ^ICMJE

INCich-07-08-7403

Study Sponsor ^ICMJE

Instituto Nacional de Cardiologia Ignacio Chavez

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:	Franklin B Mora, M.D.	Instituto Nacional de Cardiología Ignacio Chávez
Study Chair:	Luis R Mariscal, M.D.	Instituto Nacional de Cardiología Ignacio Chávez
Study Chair:	Guadalupe C De la Cruz, R.N.	Instituto Nacional de Cardiología Ignacio Chávez
Study Director:	Martha G Franco, M.D., PH.D.	Instituto Nacional de Cardiología Ignacio Chávez
Study Chair:	Héctor G Pérez-Grovas, M.D.	Instituto Nacional de Cardiología Ignacio Chávez
Study Chair:	Norma Venegas, M.D.	Centro de Hemodiálisis "Mansilla"-Buenos Aires.
Study Chair:	Carlos Z Najún, M.D.	Centro de Hemodiálisis-"Mansilla"-Buenos Aires

Information Provided By

Instituto Nacional de Cardiologia Ignacio Chavez

Verification Date

March 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP