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Preoperative Hepatic Arterial Infusion Chemotherapy

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2007 by IRCCS San Raffaele.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
IRCCS San Raffaele
ClinicalTrials.gov Identifier:
NCT00522509
First received: August 28, 2007
Last updated: NA
Last verified: May 2007
History: No changes posted

August 28, 2007
August 28, 2007
December 1995
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No Changes Posted
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Preoperative Hepatic Arterial Infusion Chemotherapy
Preoperative Hepatic Arterial Infusion Chemotherapy in Patients Undergoing Liver Resection for Colorectal Liver Metastases

To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.

Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group).

Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated.

Observational
Observational Model: Defined Population
Time Perspective: Longitudinal
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Colorectal Liver Metastases
Drug: Floxuridine FUDR
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
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Inclusion Criteria:

  • Unresectable liver metastases
  • Potentially resectable liver metastases

Exclusion Criteria:

  • Extrahepatic disease
Both
18 Years to 90 Years
No
Contact information is only displayed when the study is recruiting subjects
Italy
 
NCT00522509
Neoadjuvant HAIC
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IRCCS San Raffaele
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Principal Investigator: Luca Aldrighetti, M.D, PhD Department of Surgery - Liver Unit, Scientific Institute San Raffaele,
IRCCS San Raffaele
May 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP