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| Descriptive Information Fields | |||||
| Brief Title † | Migraine Inducing Effects and Changes in Brain Haemodynamics of PGI2 | ||||
| Official Title † | Migraine Inducing Effects and Changes in Brain Haemodynamics of PGI2 | ||||
| Brief Summary | We hypothesised that intravenous infusion of PGI2 induced headache or migraine and cranial vasodilatation in migraineurs. |
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| Detailed Description | |||||
| Study Phase | |||||
| Study Type † | Interventional | ||||
| Study Design † | Basic Science, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Efficacy Study | ||||
| Primary Outcome Measure † | Headache and accompanying symptoms. Blood flow velocity in the middle cerebral artery, diameter changes in superficial temporal artery and radial artery. [ Time Frame: 14 hours ] | ||||
| Secondary Outcome Measure † | Blood pressure, pulse [ Time Frame: 100 min ] | ||||
| Condition † | Headache Migraine Vasodilatation |
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| Intervention † | Drug: Prostacyclin, PGI2 Drug: Placebo |
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| MEDLINE PMIDs | |||||
| Links | |||||
| Recruitment Information Fields | |||||
| Recruitment Status † | Recruiting | ||||
| Enrollment † | 12 | ||||
| Start Date † | December 2006 | ||||
| Completion Date | September 2007 | ||||
| Eligibility Criteria † | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both | ||||
| Ages | 18 Years to 55 Years | ||||
| Accepts Healthy Volunteers | No | ||||
| Contacts †† |
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| Location Countries † | Denmark | ||||
| Administrative Information Fields | |||||
| NCT ID † | NCT00510172 | ||||
| Organization ID | KA-20060086 | ||||
| Secondary IDs †† | |||||
| Study Sponsor † | Glostrup University Hospital,Copenhagen | ||||
| Collaborators †† | |||||
| Investigators † |
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| Information Provided By | Glostrup University Hospital,Copenhagen | ||||
| Verification Date | July 2007 | ||||
| First Received Date † | July 30, 2007 | ||||
| Last Updated Date | July 30, 2007 | ||||