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Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules

This study has been terminated.
(The received reliability with increase in quantity of participants of research did not vary)
Sponsor:
Information provided by:
Yaroslavl State Medical Academy
ClinicalTrials.gov Identifier:
NCT00507897
First received: July 25, 2007
Last updated: February 6, 2008
Last verified: February 2008
History of Changes

July 25, 2007
February 6, 2008
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Complete list of historical versions of study NCT00507897 on ClinicalTrials.gov Archive Site
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Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules
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The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.

As opposed to widely investigated condition of cardiovascular system in patients with functional disorders of thyroid gland, the relationship between thyroid hormones and hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid hormones with the parameters of blood pressure in conditions of euthyroidism, on the other hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of patients without pathology of cardiovascular system whose increased blood pressure is connected with preoperative stress, that in turn will allow to exclude influence of the pathology of the cardiovascular system on studied correlation.
Observational
Time Perspective: Prospective
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Thyroid Nodules
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  • A
    Cohort: Patients with normal blood pressure scheduled to have thyroid nodules surgically removed
  • A1
    Patients from group A not receiving any drugs and who lack other pathology, gender and age matched group B1
  • B
    Cohort: Patients with increased blood pressure scheduled to have thyroid nodules surgically removed
  • B1
    Patients from group B not receiving any drugs and who lack other pathology, gender and age matched group A1
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
100
December 2007
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Inclusion Criteria:

  • Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria:

  • Hyperthyroidism
  • Hypothyroidism
Both
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No
Contact information is only displayed when the study is recruiting subjects
Russian Federation
 
NCT00507897
ESheverdova-1
No
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Yaroslavl State Medical Academy
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Study Chair: Yuriy Alexandrov, Professor Yaroslavl State Medical Academy
Yaroslavl State Medical Academy
February 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP