MAGIC Cell-5-Combicytokine Trial

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2007 by Seoul National University Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Seoul National University Hospital
ClinicalTrials.gov Identifier:
NCT00501917
First received: July 13, 2007
Last updated: NA
Last verified: July 2007
History: No changes posted

July 13, 2007
July 13, 2007
March 2007
Not Provided
change of left ventricular ejection fraction measured by cardiac MRI [ Time Frame: 6, 12, and 24month ]
Same as current
No Changes Posted
wall motion score index exercise capacity BNP [ Time Frame: 6,12, 24month ]
Same as current
Not Provided
Not Provided
 
MAGIC Cell-5-Combicytokine Trial
Single Center, Prospective, Randomized, Partly-Double Blinded, Controlled Trial to Assess the Safety and Feasibility of Intracoronary Cell Infusion Mobilized With G-CSF and Darbepoetin and Their Effects on Improvement of Cardiac Function in Patients With Myocardial Infarction: Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Erythropoietin Mobilization and Intra-Coronary Cell Infusion –5-Combination Cytokine Therapy Trial

Combination use of darbepoetin and G-CSF will improve left ventricular systolic function in patients with acute myocardial infarction who receive intracoronary infusion of mobilized peripheral blood stem cell in comparison with patient who treated with conventional measures and who received intracoronary infusion of mobilized peripheral blood stem cell by G-CSF alone.

Not Provided
Interventional
Phase 2
Phase 3
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Acute Myocardial Infarction
Drug: G-CSF with/without darbepoetin, peripheral blood stem cell infusion
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
116
February 2010
Not Provided

Inclusion Criteria:

  • ST elevation acute myocardial infarction
  • < 80years
  • successful revascularization of culprit vessel

Exclusion Criteria:

  • uncontrolled congestive heart failure
  • uncontrolled myocardial ischemia
  • uncontrolled ventricular arrhythmia
  • malignancy
  • serious hematologic disease
  • chronic renal failure
Both
15 Years to 80 Years
No
Contact: Hyo-Soo Kim, MD PhD 82-2-2072-2226 hyosoo@snu.ac.kr
Contact: Hyun-Jae Kang, MD PhD 82-2-2072-2279 nowkang@snu.ac.kr
Korea, Republic of
 
NCT00501917
MAGIC Cell-5
Yes
Not Provided
Seoul National University Hospital
Not Provided
Principal Investigator: Hyo-Soo Kim, MD PhD Seoul National University Hospital
Seoul National University Hospital
July 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP