Effects of Mild Hypobaric Hypoxia on Sleep and Post-Sleep Performance

This study has been completed.
Sponsor:
Collaborator:
The Boeing Company
Information provided by:
Oklahoma State University Center for Health Sciences
ClinicalTrials.gov Identifier:
NCT00498563
First received: July 9, 2007
Last updated: July 8, 2008
Last verified: July 2008

July 9, 2007
July 8, 2008
October 2006
August 2007   (final data collection date for primary outcome measure)
Quality and quantity of sleep measured by actigraphy and polysomnography Neurobehavioral performance measured by Psychomotor Vigilance Test (PVT) and Automated Neurophysiologic Assessment Metrics Battery (ANAM) [ Time Frame: 7 hours; 4 hours ]
Same as current
Complete list of historical versions of study NCT00498563 on ClinicalTrials.gov Archive Site
Mood State measured by Profile of Mood States (POMS) Symptoms of altitude illness measured by Environmental Symptoms Questionnaire (ESQ IV) and Lake Louise Symptom Scores (LLS) [ Time Frame: 20 hours ]
Same as current
Not Provided
Not Provided
 
Effects of Mild Hypobaric Hypoxia on Sleep and Post-Sleep Performance
Investigation to Determine the Effects of Mild Hypobaric Hypoxia on Sleep and Post-Sleep Neurobehavioral Performance

Hypobaric hypoxia (decreased oxygen supply to body tissues due to low atmospheric pressure) caused by exposure to high altitude disrupts sleep. Sleep deprivation is associated with degraded post-sleep performance of neurobehavioral tasks. The lowest altitude at which sleep and/or post-sleep performance are affected is not known. The study hypothesis is that sleep and/or post-sleep performance of neurobehavioral tasks will occur due to hypobaric hypoxia at altitudes of 8,000 or less.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind
Primary Purpose: Basic Science
  • Altitude
  • Hypoxia
  • Environmental Sleep Disorder
Procedure: altitude exposure in hypobaric chamber
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
34
August 2007
August 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • healthy
  • age 30 to 60 years

Exclusion Criteria:

  • sleep disorders or abnormal sleep patterns
  • mood or psychiatric disorders including claustrophobia
  • altitude exposure above 5,000 ft in the previous 2 months
  • born or raised at terrestrial altitude 5,000 ft or greater
  • conditions that would disqualify for FAA Medical Certificate
  • acute medical conditions
Male
30 Years to 60 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00498563
IRB#2006024
No
Not Provided
Oklahoma State University Center for Health Sciences
The Boeing Company
Principal Investigator: J. Michael Muhm, M.D., M.P.H. The Boeing Company
Principal Investigator: Paul B Rock, DO, PhD Oklahoma State University Center for Aerospace & Hyperbaric Medicine
Oklahoma State University Center for Health Sciences
July 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP