Atorvastatin in Moderate Active Crohns Disease

This study has been completed.
Sponsor:
Information provided by:
Skane University Hospital
ClinicalTrials.gov Identifier:
NCT00454545
First received: March 29, 2007
Last updated: October 18, 2007
Last verified: October 2007

March 29, 2007
October 18, 2007
October 2006
Not Provided
Inflammatory markers in plasma before and after treatment.
Same as current
Complete list of historical versions of study NCT00454545 on ClinicalTrials.gov Archive Site
Change in clinical activity index and mucosal inflammation after treatment.
Same as current
Not Provided
Not Provided
 
Atorvastatin in Moderate Active Crohns Disease
Not Provided

Open pilot study to collect information regarding the effect of atorvastatin on patients with active Crohns disease.

Not Provided
Interventional
Phase 2
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Crohns Disease
Drug: Atorvastatin
Not Provided
Grip O, Janciauskiene S. Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease. PLoS ONE. 2009;4(5):e5263. Epub 2009 May 6.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
12
October 2007
Not Provided

Inclusion Criteria:

  • Clinical diagnosis of Crohns disease
  • C-reactive protein level > 2 mg/L in absence of an infection
  • Fecal calprotectin > 250 mg/kg or CDAI > 150

Exclusion Criteria:

  • CDAI > 450
  • Prednisolone dosage above 15 mg/day
Both
18 Years to 65 Years
No
Contact information is only displayed when the study is recruiting subjects
Sweden
 
NCT00454545
010-02
Yes
Not Provided
Skane University Hospital
Not Provided
Principal Investigator: Olof Grip, MD, PhD Malmo University Hospital, Region Skåne
Study Chair: Anders Bredberg, MD, PhD Malmo University Hospital, Region Skåne
Study Chair: Gunnel Bredberg, MD, PhD Malmo University Hospital, Region Skåne
Skane University Hospital
October 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP