Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women

This study has been completed.
Sponsor:
Information provided by:
Mayo Clinic
ClinicalTrials.gov Identifier:
NCT00443716
First received: March 5, 2007
Last updated: January 14, 2010
Last verified: January 2010

March 5, 2007
January 14, 2010
April 1985
April 1989   (final data collection date for primary outcome measure)
efficacy of estraderm treatment on osteoporotic women
Same as current
Complete list of historical versions of study NCT00443716 on ClinicalTrials.gov Archive Site
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Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women

To evaluate the effect of estrogen treatment on adipocytic and osteoblastic parameters by histomorphometrically measuring adipocyte volume (AV/TV) and adipocyte numbers in goldner's stained iliac crest bone biopsy specimens collected from subjects recruited in the study (IRB number 21B85). The adipocytic parameters will be then correlated with osteoblastic parameters obtained previously during the course of the initai study involving the effect of transdermal estrogen on bone turnover in postmenopausal osteoporotic women.

Not Provided
Interventional
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Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Osteoporosis
  • Postmenopausal
Drug: estrogen
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Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
60
April 1989
April 1989   (final data collection date for primary outcome measure)

Post-menopausal osteoporotic women

Female
30 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00443716
05-004111, 21b85
Yes
Not Provided
Mayo Clinic
Not Provided
Principal Investigator: B. Lawrence Riggs, M.D. Mayo Clinic
Mayo Clinic
January 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP