Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema - Tabular View

Tracking Information

First Received Date ^ICMJE

February 28, 2007

Last Updated Date

February 28, 2007

Start Date ^ICMJE

May 2007

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Improvement of dyshidrotic hand eczema in the study period.

Original Primary Outcome Measures ^ICMJE

Same as current

Change History

No Changes Posted

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Official Title ^ICMJE

Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Brief Summary

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

Detailed Description

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.

The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Study Phase

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study

Condition ^ICMJE

Vesicular Palmoplantar Eczema
Pompholyx

Intervention ^ICMJE

Drug: dandelion juice marketed as a dietary supplement in Denmark

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Not yet recruiting

Enrollment ^ICMJE

Completion Date

May 2007

Primary Completion Date

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

Exclusion Criteria:

Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
Pregnancy, lactation.
Compositae contact allergy.
Liver or gall bladder disease.
Abnormal renal or hepatic blood tests.

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact: Evy Paulsen, Dr.

+6541 2705

evy.paulsen@regionsyddanmark.dk

Location Countries ^ICMJE

Denmark

Administrative Information

NCT ID ^ICMJE

NCT00442091

Responsible Party

Study ID Numbers ^ICMJE

20070010

Study Sponsor ^ICMJE

Odense University Hospital

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

Evy Paulsen, Dr.

Department of Dermatology, Odense University Hospital, DK-5000 Odense C

Information Provided By

Odense University Hospital

Verification Date

February 2007

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP