Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2009 by Radboud University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Radboud University
ClinicalTrials.gov Identifier:
NCT00441753
First received: February 28, 2007
Last updated: February 5, 2009
Last verified: February 2009

February 28, 2007
February 5, 2009
September 2006
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Complete list of historical versions of study NCT00441753 on ClinicalTrials.gov Archive Site
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Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest
Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest

Survivors of a cardiac arrest frequently develop severe postanoxic encephalopathy. Derangements in cerebral blood after return of spontaneous circulation play an important role in the pathogenesis of postanoxic encephalopathy. In the present study we examine the effect of mild therapeutic hypothermia on cerebral blood flow and carbondioxide reactivity in patients after cardiac arrest.

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Observational
Observational Model: Cohort
Time Perspective: Prospective
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Probability Sample

Patients after cardiac arrest, comatose and treated with therapeutic hypothermia

  • Cardiac Arrest
  • Post-Anoxic Encephalopathy
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
10
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Inclusion Criteria:

  • adult patients
  • GCS after return of circulation < 7
  • Induced mild hypothermia for 24 hours
  • primary rhythm ventricular fibrillation

Exclusion Criteria:

  • Thrombolysis
  • Cardiogenic shock with expected survival < 24 hrs
  • Pregnancy
  • No informed consent
Both
18 Years to 95 Years
No
Contact: Cornelia Hoedemaekers, MD PhD 00.31.24.3617273 C.Hoedemaekers@ic.umcn.nl
Netherlands
 
NCT00441753
KSCH0601
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Radboud UNiversity Nijmegen Medical Centre
Radboud University
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Principal Investigator: Cornelia Hoedemaekers, MD PhD Radboud University
Study Director: Johannes van der Hoeven, MD PhD Radboud University
Radboud University
February 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP