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Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

This study has been completed.
Sponsor:
Information provided by:
Centre Hospitalier Universitaire de Saint Etienne
ClinicalTrials.gov Identifier:
NCT00428779
First received: January 29, 2007
Last updated: June 10, 2009
Last verified: June 2009
History of Changes

January 29, 2007
June 10, 2009
September 2007
December 2007   (final data collection date for primary outcome measure)
-Voluntary and electrically evoked forces on the contracted muscles [ Time Frame: 24 hours ] [ Designated as safety issue: No ]
-Voluntary and electrically evoked forces on the contracted muscles
Complete list of historical versions of study NCT00428779 on ClinicalTrials.gov Archive Site
  • Electrically evoked forces on the relaxed muscles and associated EMG activity [ Time Frame: 24 hours ] [ Designated as safety issue: No ]
  • Blood samples before the exercise [ Time Frame: every 4 hours ] [ Designated as safety issue: No ]
  • Muscle biopsy (vastus lateralis) [ Time Frame: before and after the exercise ] [ Designated as safety issue: No ]
  • Electrically evoked forces on the relaxed muscles and associated EMG activity
  • Blood samples before the exercise and every 4 hours.
  • Muscle biopsy (vastus lateralis) before and after the exercise
Not Provided
Not Provided
 
Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise
Neuromuscular and Cognitive Fatigue During a 24h Treadmill Running Exercise.

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.
Interventional
Not Provided
Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Healthy
  • Procedure: running during 24 hours without sleep
    patients running during 24 hours without sleep
  • Other: no sleeping
    patients without sleep during 24 hours
  • Experimental: 1
    patients running during 24 hours without sleep
    Intervention: Procedure: running during 24 hours without sleep
  • Placebo Comparator: 2
    patients without sleep during 24 hours
    Intervention: Other: no sleeping

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
30
December 2007
December 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
  • The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion Criteria:

  • The subjects will not be selected if:

    • they were injured in the 3 months before the experiment
    • they had a tendon or joint pathology that could impair strength measurements.
    • they participate to an other experiment at the same time
Both
18 Years to 60 Years
Yes
Contact information is only displayed when the study is recruiting subjects
France
 
NCT00428779
0601095, DGS 2006-0111, 2006-A00312-49
No
Clément CAILLAUX, CHU de Saint-Etienne
Centre Hospitalier Universitaire de Saint Etienne
Not Provided
Study Chair: DENIS Christian, Professor Service de médecine du sport, CHU SAINT-ETIENNE
Centre Hospitalier Universitaire de Saint Etienne
June 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP