Long-Term IOP Fluctuation and VF Progression After Triple Procedure

This study has been completed.
Sponsor:
Information provided by:
Yonsei University
ClinicalTrials.gov Identifier:
NCT00428740
First received: January 29, 2007
Last updated: NA
Last verified: January 2007
History: No changes posted

January 29, 2007
January 29, 2007
October 2005
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No Changes Posted
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Long-Term IOP Fluctuation and VF Progression After Triple Procedure
Long-Term Intraocular Pressure Fluctuation and Visual Field Progression in Glaucoma Patients With Low Intraocular Pressure After Triple Procedure

Long-term intraocular pressure (IOP) fluctuation may be significantly associated with the progression of glaucomatous visual field loss, even in patients kept always low IOP after triple procedure, an effective approach for patients with coexisting glaucoma and visually significant cataracts.

Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in glaucoma patients. However, even if the IOP can been substantially lowered, reduction of mean and peak IOP does not always prevent visual field progression.We believe that the long-term IOP fluctuation may play a significant role in visual field deterioration in those patients.

Observational
Observational Model: Defined Population
Time Perspective: Longitudinal
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  • Glaucoma
  • Filtering Surgery
  • Intraocular Pressure
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Hong S, Seong GJ, Hong YJ. Long-term intraocular pressure fluctuation and progressive visual field deterioration in patients with glaucoma and low intraocular pressures after a triple procedure. Arch Ophthalmol. 2007 Aug;125(8):1010-3.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
300
December 2005
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Inclusion Criteria:

  1. Underwent triple procedure
  2. At leas 3 years of follow-up after surgery
  3. IOP <18mmHg at each postoperative visit
  4. A minimum of 5 visual field examinations
  5. A reference visual field defect score of 16 or less
  6. Good reliability indices of visual field

Exclusion Criteria:

  1. Any other significant ocular diseases or intraocular surgical histories,
  2. Diseases that may affect visual field or diabetes
Both
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No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT00428740
3-2006-0388
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Yonsei University
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Principal Investigator: Gong Je Seong, MD, PhD Yondgong Severance Hospital, Yonsei University College of Medicine
Yonsei University
January 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP