Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment

This study has been completed.
Sponsor:
Information provided by:
DBL -Institute for Health Research and Development
ClinicalTrials.gov Identifier:
NCT00414479
First received: December 20, 2006
Last updated: January 13, 2010
Last verified: January 2010

December 20, 2006
January 13, 2010
July 2006
January 2010   (final data collection date for primary outcome measure)
hemoglobin level
Not Provided
Complete list of historical versions of study NCT00414479 on ClinicalTrials.gov Archive Site
  • Schistosomiasis infection
  • malaria infection
  • iron deficiency
Not Provided
Not Provided
Not Provided
 
Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment
Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment

The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).

The study will be carried out in an area around Lake Victoria in Kenya where the prevalence of schistosomiasis and malaria are highest in the areas nearest to the Lake. Depending on the prevalence of schistosomiasis a sample of between 876 to 2.524 children will be enrolled in the study. The children who will be in the age between 9 to 12 year, will have their stool and urine examined for schistosomiasis and intestinal worms and a blood sample will be examined for malaria parasites and the hemoglobin level. Children will also be weight, measured and examined by a doctor and register their food intake over one week, to determine their nutritional status. Children who are found to be infected with schistosomiasis, intestinal worms or malaria will be offered treatment. Children who are found to have anemia will be offered a course of iron supplementation, children with severe anemia will be referred to the nearest health facility for treatment. 12 months after the initial examinations and treatment all children will have a re-examination of their stool, urine and blood.

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

children 9-12 years of age

  • Anaemia
  • Schistosomiasis Infection
  • Malaria
  • Iron Deficiency
Drug: praziquantl, iron, ACT
children 9-12 years of age
Children with schistosomiasis, malaria and anaemia
Intervention: Drug: praziquantl, iron, ACT
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1500
January 2010
January 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • school children between 9 to 12 year
Both
9 Years to 12 Years
No
Contact information is only displayed when the study is recruiting subjects
Kenya
 
NCT00414479
SRP-KY-DK-06
Not Provided
Not Provided
DBL -Institute for Health Research and Development
Not Provided
Principal Investigator: Diana Karanja, DR Kenya Medical Research Institute
DBL -Institute for Health Research and Development
January 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP