Insulin Infusion in the Hospital Wards

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Guillermo Umpierrez, Emory University
ClinicalTrials.gov Identifier:
NCT00412347
First received: December 14, 2006
Last updated: February 7, 2014
Last verified: February 2014

December 14, 2006
February 7, 2014
August 2006
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Complete list of historical versions of study NCT00412347 on ClinicalTrials.gov Archive Site
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Insulin Infusion in the Hospital Wards
Insulin Infusion and Outcomes for Non-Critical Wards

Increasing evidence from clinical studies in Intensive Care Unit (ICU) settings indicates that insulin infusion can improve outcome measures for patients with hyperglycemia (high blood sugar) independent of a previous diagnosis of diabetes mellitus. This improvement in health could also apply to patients that have high blood sugars in various other non-critical care areas of the hospital as well. However, the data that shows improvement in health outcomes has been collected from wards that have a lower patient to provider and patient to nurse ratio, resulting in the ability for a much tighter control of the insulin infusion. We hypothesize that tight blood glucose control will provide the same benefits for patients in non-intensive care units settings but that these protocols may lead to a higher incidence of hypoglycemia (low blood sugar) and potentially to adverse outcomes in patients.

This study aims to determine the clinical outcome of patients treated with insulin infusion as well as the rate of hypoglycemic episodes in non-intensive areas. We will conduct a chart review of patients treated with insulin infusions in non-critical wards at Emory University Hospital during the period of 7/1/04 to 6/30/05. Medical records of all patients treated with intravenous insulin infusion protocols will be analyzed. Data on demographics, laboratory values, mortality rate, rate of hypoglycemic events, length of stay, as well as disposition at discharge will be analyzed.

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Observational
Time Perspective: Retrospective
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Non-Probability Sample

Cohort of hospitalized adult subjects in a teaching institution.

Hyperglycemia
Drug: Insulin Drip Therapy
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Smiley D, Rhee M, Peng L, Roediger L, Mulligan P, Satterwhite L, Bowen P, Umpierrez GE. Safety and efficacy of continuous insulin infusion in noncritical care settings. J Hosp Med. 2010 Apr;5(4):212-7. doi: 10.1002/jhm.646.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
200
December 2006
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Inclusion Criteria:

  • All subjects over 18 years of age that received intravenous insulin treatment on general medical and surgical wards at Emory University Hospital during the period of 7/1/2004 to 6/30/2005
Both
19 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00412347
1203-2005, 1203-2005
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Guillermo Umpierrez, Emory University
Emory University
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Principal Investigator: Guillermo Umpierrez, MD Emory University
Emory University
February 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP