Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy - Tabular View

Tracking Information

First Received Date ^ICMJE

November 27, 2006

Last Updated Date

May 21, 2008

Start Date ^ICMJE

March 2006

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Original Primary Outcome Measures ^ICMJE

VISA-p score [ Time Frame: half year ]

Change History

Complete list of historical versions of study NCT00404469 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Tendon Biomechanics [ Time Frame: 12 weeks ]

Descriptive Information

Brief Title ^ICMJE

Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Official Title ^ICMJE

Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Brief Summary

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Detailed Description

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Study Phase

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Basic Science, Randomized, Single Blind (Investigator), Active Control, Parallel Assignment

Condition ^ICMJE

Patellar Tendinopathy / Jumpers Knee

Intervention ^ICMJE

Procedure: peritendinous corticosteroid injections
Procedure: eccentric decline squat training
Procedure: heavy slow resistance training

Study Arms / Comparison Groups

Active Comparator: Peritendinous corticosteroid injections at 0 and 4 weeks. 12 weeks total
Experimental: 12 weeks of eccentric unilateral decline squats
Experimental: Heavy slow resistance training. 3/week. 12 weeks

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

November 2007

Primary Completion Date

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Clinical patellar tendinopathy pain.
Tendon swelling
Hypoechoic
Doppler activity in tendon

Exclusion Criteria:

Previous knee surgery
diabetes
arthritis
previous steroid injections

Gender

Male

Ages

18 Years to 55 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

Denmark

Administrative Information

NCT ID ^ICMJE

NCT00404469

Responsible Party

Study ID Numbers ^ICMJE

Patellar tendinopathy

Study Sponsor ^ICMJE

Bispebjerg Hospital

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

Mads Kongsgaard, PhD., MSc.

Institute of Sports Medicine Copenhagen

Information Provided By

Bispebjerg Hospital

Verification Date

May 2008

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP