Renal Artery Calcium and Hypertension - Tabular View

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Renal Artery Calcium and Hypertension

This study is not yet open for participant recruitment.
Information provided by Hadassah Medical Organization

This Tabular View shows the required WHO registration data elements as marked by ^†

Descriptive Information Fields

Brief Title ^†

Renal Artery Calcium and Hypertension

Official Title ^†

Calcifications of the Renal Arteries and Renal Artery Stenosis in Patients With and Without Hypertension?

Brief Summary

CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and coronary arteries are good predictor for obstructive atherosclerotic disease.Stenosis of the renal arteries can cause symptomatic or asymptomatic hypertension with subsequent clinical sequelae. Therefore early diagnosis of this condition is imperative.

The goal of our study is to investigate the correlation between incidental calcifications of the renal arteries in CT examinations and the presence of actual stenosis of these vessels in patients with and without hypertension.

Detailed Description

Every patient aged 30-100 referred for abdominal CT examination with IV contrast injection will be included in this study (total 300 patients.Prior to the examination relevant clinical data including history of hypertension and predisposing conditions for atherosclerotic disease, will be investigated. The patient will undergo conventional CT with no special procedures. The images will be review by the radiologist for the presence of renal arteries calcifications, renal arteries stenosis,plaque location, plaque burden and characterization and secondary renal pathology.

This study will not change the examination technique and is not associated with any inconvenience to the patients.

Study Phase

Study Type ^†

Observational

Study Design ^†

Screening, Longitudinal, Defined Population, Prospective Study

Primary Outcome Measure ^†

Secondary Outcome Measure ^†

Condition ^†

Hypertension
Atherosclerosis

Intervention ^†

MEDLINE PMIDs

Links

Recruitment Information Fields

Recruitment Status ^†

Not yet recruiting

Enrollment ^†

300

Start Date ^†

November 2006

Completion Date

Eligibility Criteria ^†

Inclusion Criteria:

Every patient referred fo abdominal CT aged 30-100

Exclusion Criteria:

Contraindication for IV contrast injection failure to demonstrate renal arteries with contrast refusal to sign an informed consent

Gender

Both

Ages

30 Years and older

Accepts Healthy Volunteers

Contacts ^††

Contact: Nurith Hiller, MD

972-50-7874980

hiller@netvision.net.il

Location Countries ^†

Israel

Administrative Information Fields

NCT ID ^†

NCT00388869

Organization ID

HILLER-HMO-CTIL

Secondary IDs ^††

Study Sponsor ^†

Hadassah Medical Organization

Collaborators ^††

Investigators ^†

Principal Investigator:

Nurith Hiller, MD

Hadassah Medical Organization, Jerusalem, Israel

Information Provided By

Hadassah Medical Organization

Verification Date

October 2006

First Received Date ^†

October 15, 2006

Last Updated Date

October 16, 2006

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.