Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

This study has been completed.
Sponsor:
Information provided by:
Fourth Military Medical University
ClinicalTrials.gov Identifier:
NCT00368407
First received: August 23, 2006
Last updated: NA
Last verified: April 2005
History: No changes posted

August 23, 2006
August 23, 2006
April 2005
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No Changes Posted
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Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck
Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

To determine the optimal treatment frequency of 308-nm excimer laser for vitiligo and identify the key clinical variable(s) associated with the treatment efficiency under the optimal treatment frequency.

Prospective, randomized, comparative study among groups of vitiligo patients treated with 308-nm excimer laser, with the limitation of no follow-up.

Vitiligo patients were treated with 308-nm excimer laser for 20 sessions at different frequencies (0.5×, 1.0×, 2.0× and 3.0× weekly). Treatment protocols adapted the dose to the lesions and not to the minimal erythemal dose. Treatment efficacy was blindly evaluated by 2 independent physicians. Re-pigmentation rate was graded on a 6-point scale. The onset of re-pigmentation of vitiligo lesions was evaluated after 5 treatment sessions. The differences between Group 0.5×, 1.0×, 2.0× and 3.0× linking different clinical variables were assessed.

Observational
Allocation: Random Sample
Primary Purpose: Screening
Time Perspective: Longitudinal
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Vitiligo
Device: 308-nm excimer laser
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Hofer A, Hassan AS, Legat FJ, Kerl H, Wolf P. Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo patients. Br J Dermatol. 2005 May;152(5):981-5.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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July 2006
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Inclusion Criteria:

  • older than 2 years, stable vitiliginous patches during the past 3 months with surfaces of at least 4cm2, and an understanding of all information given by signing a written consent form.

Exclusion Criteria:

  • pregnant or breastfeeding women; personal history of a hypertrophic scar, skin cancer; taking immunosuppressive or photosensitizing drugs and undergoing phototherapy during the past 3 months.
Both
2 Years to 60 Years
No
Contact information is only displayed when the study is recruiting subjects
China
 
NCT00368407
fmmu200504
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Fourth Military Medical University
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Study Director: gao tianwen, MD,PHD Ddepartment of Dermatology
Fourth Military Medical University
April 2005

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP