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Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan
This study has been suspended.
( no patient was recruited till 1/2008 )
Study NCT00345306   Information provided by Hadassah Medical Organization
First Received: June 27, 2006   Last Updated: May 6, 2008   History of Changes

June 27, 2006
May 6, 2008
March 2007
 
Pregnancy rates
Same as current
Complete list of historical versions of study NCT00345306 on ClinicalTrials.gov Archive Site
Lutheal hormonal profile
Same as current
 
Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan
Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan - a Clinical Comparative Study

The transfer of frozen-thawed embryos can be performed in a natural ovulatory cycle or in a hormonally manipulated cycle with a comparable pregnancy rate of 15%-20% per ET. When a hormonally modulated ET cycle is scheduled,an artificial endometrial preparation is carried out using estrogen stimulation followed by a concomitant progesterone treatment. Two progestative drugs are currently used in conventional IVF treatment, Utrogetan and Endometrin. Although Endometrin has been be efficiently used to support the luteal phase after embryo transfer in IVF cycles, currently, there is no study that assess its efficacy for clinical use in frozen-thawed ET cycles. The present study aims to compare the outcome of frozen thawed ET cycles when either Endometrin or Utrogestan are used as the progestative substitution in an artificially prepared endometrium.

 
Phase IV
Interventional
Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Frozen Thawed Embryo Transfer
Drug: Comparison between two different progesterone administration
 
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Suspended
120
 
 

Inclusion Criteria:

  1. Patients undergoing frozen thawed ET cycles
  2. Patient has at least two embryos suitable for transfer after thawing
  3. Age 18-35 years -

Exclusion Criteria:

  1. Any known sensitivity to Endometrin or Utrogestan
  2. Endometrial thickness less than 7.5 mm after estrogen priming -
Female
18 Years to 35 Years
 
Contact information is only displayed when the study is recruiting subjects
Israel
 
NCT00345306
 
EndoUtro-HMO-CTIL
Hadassah Medical Organization
 
Principal Investigator: Alex Simon Hadassah University Hospital
Hadassah Medical Organization
June 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP