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A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Alcon Research
ClinicalTrials.gov Identifier:
NCT00314171
First received: April 10, 2006
Last updated: March 2, 2012
Last verified: March 2012

April 10, 2006
March 2, 2012
October 2005
August 2007   (final data collection date for primary outcome measure)
Mean IOP
Not Provided
Complete list of historical versions of study NCT00314171 on ClinicalTrials.gov Archive Site
Percent patients with IOP < 18 mmHg
Not Provided
Not Provided
Not Provided
 
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.

Not Provided
Interventional
Phase 3
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
  • Open-angle Glaucoma
  • Ocular Hypertension
  • Drug: Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension
    One drop in the study eye(s) twice daily for 12 months
  • Drug: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
    One drop in the study eye(s) twice daily for 12 months
    Other Name: COSOPT
  • Experimental: Brinzolamide + Timolol
    Intervention: Drug: Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension
  • Active Comparator: Dorzolamide + Timolol
    Intervention: Drug: Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
437
August 2007
August 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 18 years or older
  • Diagnosis of open-angle glaucoma or ocular hypertension
  • Other protocol-defined inclusion criteria may apply

Exclusion Criteria:

  • Under 18
  • Pregnant
  • Other protocol-defined exclusion criteria may apply
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00314171
C-05-10
No
Alcon Research
Alcon Research
Not Provided
Not Provided
Alcon Research
March 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP