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The Effect of Mild Traumatic Brain Injury on Recovery From Injury
This study has been completed.
Study NCT00295074   Information provided by University of Pittsburgh
First Received: February 17, 2006   Last Updated: February 7, 2008   History of Changes

February 17, 2006
February 7, 2008
October 2004
 
  • functional outcome
  • subjective symptoms
Same as current
Complete list of historical versions of study NCT00295074 on ClinicalTrials.gov Archive Site
 
same
 
The Effect of Mild Traumatic Brain Injury on Recovery From Injury
The Effect of Mild Traumatic Brain Injury on Recovery From Injury

Mild traumatic brain injury (TBI) is a common injury that can produce significant functional sequelae and ongoing disabling symptoms. Predicting who will have an uncomplicated recovery and who will suffer ongoing symptoms is difficult. This protocol evaluates the use of neuropsychologic testing after mild TBI in injured patients to attempt to objectively establish predictors of long term disability and functional recovery.

Patients who are hospitalized and who have suffered mild TBI (loss of consciousness or post-traumatic amnesia; Glasgow Coma Score 13-15; admitted within 24 hours of injury; able to read, speak, and understand English) who do not have pre-injury dementia or significant cognitive impairment will undergo computerized neuropsychologic testing using a previously validated tool that has been effective in sports-related mild TBI. Sequential testing will be performed during recovery and patients who report disabling symptoms and/or functional impairment will be compared to patients who recover uneventfully. Goal is to identify those parameters that predict early who may suffer long term sequelae or functional impairment and therefore benefit from early cognitive rehabilitation. Secondary goals are to establish objective parameters for functional recovery after mild TBI.

 
Interventional
Diagnostic, Non-Randomized, Open Label, Active Control, Single Group Assignment, Efficacy Study
  • Traumatic Brain Injury
  • Trauma
  • Head Injury
  • Brain Concussion
Procedure: neuropsychologic testing
 
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Completed
800
September 2007
 

Inclusion Criteria:

  • Mild TBI
  • Admitted within 24 hours of injury
  • Able to read, speak,and understand English

Exclusion Criteria:

  • Expected to die of their injuries
  • Pre-existing dementia or significant cognitive impairment
  • Neurologically impaired and incapable of completing testing
  • Physically incapable of using arms/hands to complete computerized testing
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00295074
 
0402095
University of Pittsburgh
 
Principal Investigator: Brian G Harbrecht, MD University of Pittsburgh
University of Pittsburgh
February 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP