Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole

This study has been completed.
Sponsor:
Information provided by:
Radboud University
ClinicalTrials.gov Identifier:
NCT00268554
First received: December 21, 2005
Last updated: March 27, 2008
Last verified: March 2008

December 21, 2005
March 27, 2008
December 2005
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forearm blood flow
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Complete list of historical versions of study NCT00268554 on ClinicalTrials.gov Archive Site
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Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole
Enhancement of Postocclusive Reactive Hyperaemia

The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.

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Interventional
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Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
  • Hyperemia
  • Hypoxia
  • Drug: dipyridamole
  • Drug: caffeine
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
12
July 2006
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Inclusion Criteria:

  • healthy volunteers between 18 and 50 years

Exclusion Criteria:

  • none specified
Both
18 Years to 50 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Netherlands
 
NCT00268554
PORH-dipy
Yes
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Radboud University
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Principal Investigator: Gerard Rongen, MD,PhD Radboud University
Radboud University
March 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP