Prevalence and Clinical Spectrum of the 22q11 Deletion

This study has been terminated.
(sufficient data collected)
Sponsor:
Information provided by:
Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier:
NCT00267397
First received: December 19, 2005
Last updated: May 2, 2007
Last verified: May 2007

December 19, 2005
May 2, 2007
January 1967
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Complete list of historical versions of study NCT00267397 on ClinicalTrials.gov Archive Site
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Prevalence and Clinical Spectrum of the 22q11 Deletion
Prevalence and Clincial Spectrum of the 22q11 Deletion: A Population Based Study of Children and Congenital Heart Defects

The purpose of this project is to conduct population based surveillance for prenatally diagnosed congenital defects amount residents of the five counties to: improve the comprehensiveness of the Metropolitan Atlanta Congenital Defects Program (MACDP) to (1) better fulfill its objectives (2) allow assessment of the impact of prenatal diagnosis and elective termination on the birth prevalence of congenital defects in Atlanta (3) develop a registry of prenatally diagnosed defects to be used in epidemiologic and genetic studies, in evaluation prevention programs and in monitoring prenatal diagnostic technology.

Since 1967, The Centers for Disease Control and Prevention (CDC) has conducted surveillance of birth defects in metropolitan Atlanta through review of hospital delivery and newborn medical records and records from various other medical sources in the five central counties of the metropolitan area (Clayton, Cobb, DeKalk, Fulton and Gwinnett, and has been expanded to include prenatal records. The project was begun n the aftermath of thalidomide and rubella epidemics as a kind of early-warning system for new or resurgent teratogens. The voluntary participation of Atlanta hospitals was sought and obtained at the inception of the system (the original system was a joint effort of the CDC, the Georgia Institute of Mental Health and Emory University).

A case must be diagnosed by the child's sixth birthday or within six years of the date of elective termination.

Children's Healthcare is one retrospective source of medical records reviewed for discharge summaries and disease indices.

Observational
Observational Model: Defined Population
Time Perspective: Longitudinal
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Congenital Disorders
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
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December 2006
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Inclusion Criteria:

  • birth defect diagnosed by the child's sixth birthday
  • birth defect diagnosed within 6 years of the elective date of termination

Exclusion Criteria:

  • those who do not meet inclusion criteria
Both
up to 6 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00267397
01-107
No
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Children's Healthcare of Atlanta
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Principal Investigator: Robert M. Campbell, MD Children's Healthcare of Atlanta
Children's Healthcare of Atlanta
May 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP