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| Descriptive Information Fields | |||||
| Brief Title † | Brain Aging Project--Kansas University | ||||
| Official Title † | KU Brain Aging Project | ||||
| Brief Summary | The purpose of this study is to determine the effects of exercise and cardiorespiratory fitness on age-related brain changes. |
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| Detailed Description | The mission of the KU Brain Aging Project is to promote healthy brain aging. How the brain changes with age is not well-characterized and even less is known about the factors influencing the rate of brain aging. Thus, we are using MRI scans to examine the structure of the brain in relation to important lifestyle factors. This will allow us to better understand the processes influencing the brain as it ages. In turn, this will help identify specific ways to promote healthy brain aging and, perhaps, prevent the onset of Alzheimer's disease. Participants complete 4 visits over several months. The first visit entails a clinical evaluation and memory testing involving the use of paper and pencil testing. The second visit is an MRI brain scan which lasts approximately one hour. The third visit involves drawing blood for laboratory testing and blood banking for future lab studies, lasting roughly 4 hours. The glucose tolerance test is administered. The fourth and final visit is an assessment of the participant's metabolism and exercise testing. This visit lasts approximately two hours. |
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| Study Phase | |||||
| Study Type † | Observational | ||||
| Study Design † | Longitudinal, Defined Population, Prospective Study | ||||
| Primary Outcome Measure † | |||||
| Secondary Outcome Measure † | |||||
| Condition † | Alzheimer's Disease | ||||
| Intervention † | |||||
| MEDLINE PMIDs | |||||
| Links | KU Brain Imaging Project ![]() |
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| Recruitment Information Fields | |||||
| Recruitment Status † | Recruiting | ||||
| Enrollment † | 120 | ||||
| Start Date † | November 2004 | ||||
| Completion Date | |||||
| Eligibility Criteria † | Inclusion Criteria:
Exclusion Criteria:
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| Gender | Both | ||||
| Ages | 65 Years and older | ||||
| Accepts Healthy Volunteers | Yes | ||||
| Contacts †† |
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| Location Countries † | United States | ||||
| Administrative Information Fields | |||||
| NCT ID † | NCT00267124 | ||||
| Organization ID | IA0089 | ||||
| Secondary IDs †† | 1R03AG026374-01 | ||||
| Study Sponsor † | National Institute on Aging (NIA) | ||||
| Collaborators †† | University of Kansas | ||||
| Investigators † |
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| Information Provided By | National Institute on Aging (NIA) | ||||
| Verification Date | September 2007 | ||||
| First Received Date † | December 16, 2005 | ||||
| Last Updated Date | September 19, 2007 | ||||