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Care Management for Patients With Alzheimer Disease and Their Family Caregivers

This study has been completed.
Information provided by Agency for Healthcare Research and Quality (AHRQ)

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Descriptive Information Fields
Brief Title  Care Management for Patients With Alzheimer Disease and Their Family Caregivers
Official Title  A Program of Collaborative Care for Alzheimer Disease
Brief Summary

This is a clinical trial to test the effectiveness of current guideline for the care of older adults with Alzheimer's disease. The study focuses on the primary care setting using a nurse care manager to facilitate guideline-level care. We are hypothesizing that patients who receive guideline-level care will have fewer behavioral problems than those who receive the usual care provided in primary care settings

Detailed Description

The specific aim of this proposal is to conduct a four-year randomized controlled clinical trial to test the efficacy of an integrated program of collaborative care as compared to usual care in improving the process and outcomes of care for older adults with dementia in a primary care setting. The program involves three primary components: (1) A comprehensive screening and diagnosis program in which all older adults aged 65 and older from Wishard’s Community Health Centers will be screened for dementia. Patients with evidence of dementia will receive further evaluation to determine an explicit diagnosis. Roudebush VA Medical Center patients aged 65 and older with a diagnosis of dementia will receive further evaluation to determine an explicit diagnosis. (2) A multidisciplinary team approach to care for patients with dementia. This care will be coordinated through a geriatric nurse practitioner or a clinical nurse specialist working in the primary care clinic. The team includes primary care and specialist physicians, psychologist, other health care workers, and relevant social service agencies working to adhere to recommended standards of care for primary care patients with dementia. (3) A proactive longitudinal tracking program in which objective measures of process and outcomes of care are fed back to the collaborative care team so that appropriate changes in the course of therapy can be undertaken.

Although authoritative guidelines for the care of patients with Alzheimer Disease and related disorders have been published, there are no clinical trials that test the impact of close adherence to these guidelines on the outcomes of care for a group of vulnerable older adults in an urban primary care setting. We are hypothesizing that patients with dementia and their caregivers who are exposed to this program will: (1) be more likely to receive the emerging standard of care for dementia, including an explicit diagnosis of dementia and an appropriate level of evaluation, education, and management; (2) be less impaired by psychopathology and behavior disturbances; (3) be less functionally impaired at 1-year and 2-year follow-up.

Study Phase
Study Type  Interventional
Study Design  Treatment, Randomized, Single Blind, Active Control, Single Group Assignment, Efficacy Study
Primary Outcome Measure  Neuropsychiatric Inventory
Cornell Depression in Dementia Scale
Activities of Daily Living
Secondary Outcome Measure  Nursing home placement
hospitalization
Condition  Alzheimer's Disease
Dementia
Intervention  Behavioral: care management
MEDLINE PMIDs 16684985
Links
Recruitment Information Fields
Recruitment Status  Completed
Enrollment  220
Start Date  August 2001
Completion Date August 2005
Eligibility Criteria 

Inclusion Criteria:

  • Alzheimers Disease

Exclusion Criteria:

  • Inability to understand English
  • No telephone
Gender Both
Ages 65 Years and older
Accepts Healthy Volunteers No
Contacts ††
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00246896
Organization ID RO1 HS10884
Secondary IDs ††
Study Sponsor  Agency for Healthcare Research and Quality (AHRQ)
Collaborators ††
Investigators 
Principal Investigator:     Christopher M. Callahan, M.D.     Indiana University    
Information Provided By Agency for Healthcare Research and Quality (AHRQ)
Verification Date October 2005
First Received Date  October 28, 2005
Last Updated Date July 26, 2006

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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