Extension Study to Assess Tolerability and Safety of Enteric-coated Mycophenolate Sodium in Renal Transplant Recipients Who Received Mycophenolate Mofetil

This study has been completed.
Sponsor:
Information provided by:
Novartis
ClinicalTrials.gov Identifier:
NCT00238966
First received: October 12, 2005
Last updated: January 28, 2011
Last verified: January 2011

October 12, 2005
January 28, 2011
November 2002
April 2005   (final data collection date for primary outcome measure)
Safety/tolerability based on adverse events within 6 months after switching patients from MMF to optimized enteric-coated mycophenolate sodium.
Not Provided
Complete list of historical versions of study NCT00238966 on ClinicalTrials.gov Archive Site
  • Safety based on renal function within 6 months after medication switch.
  • Pharmacokinetics (PK) in a randomized subpopulation.
  • Efficacy measured by the incidence of biopsy-proven acute rejection, graft loss or death within 6 months post medication switch.
  • Efficacy measured by the incidence of biopsy-proven acute rejection 6 months post medication switch.
  • Graft survival and patient survival 6 months post medication switch.
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Extension Study to Assess Tolerability and Safety of Enteric-coated Mycophenolate Sodium in Renal Transplant Recipients Who Received Mycophenolate Mofetil
A One Arm, Open-label Study to Investigate the Tolerability and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in Renal Transplant Recipients Who Received Mycophenolate Mofetil (MMF)

This extension study is considered to allow patients being treated with EC-MPS to collect further information on the long-term safety of this drug.

Not Provided
Interventional
Phase 4
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
Renal Transplantation
Drug: Enteric-Coated Mycophenolate Sodium (EC-MPS)
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
187
April 2005
April 2005   (final data collection date for primary outcome measure)

Inclusion/ Exclusion criteria

- Only patients who were participating in study CERL080A2405-DE02 and have completed the first 6 months of the core study can be included in this additional extension study.

Other protocol-defined inclusion/exclusion criteria may apply.

Both
18 Years to 75 Years
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Contact information is only displayed when the study is recruiting subjects
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NCT00238966
CERL080A2405DE02E1
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Novartis
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Study Director: Novartis Novartis
Novartis
January 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP