Optimal Timing for Repair of Left to Right Shunt Lesions

This study has been terminated.
(sufficient data was collected)
Sponsor:
Information provided by:
Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier:
NCT00229827
First received: September 13, 2005
Last updated: March 14, 2012
Last verified: May 2007

September 13, 2005
March 14, 2012
May 2005
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Complete list of historical versions of study NCT00229827 on ClinicalTrials.gov Archive Site
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Optimal Timing for Repair of Left to Right Shunt Lesions
Optimal Timing for Repair of Left-to-Right Shunt Lesions

The purpose of this study is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.

In the past, children with left-to-right shunt lesions such as ventricular septal defects and atrioventricular canal defects were palliated with a pulmonary artery band. This prevented injury to the pulmonary vasculature while the child grew to a size where complete repair could be undertaken. With the improvements in surgical technique and critical care, there is a push to do a primary complete repair for these defects at younger and younger ages. These operations should be delayed as long as possible to allow for growth but not so long that there is unnecessary heart failure and medication requirements. The primary aim is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals. The secondary aim is to define the criteria for failing medical anti-congestive heart failure therapy. This study will be conducted through a retrospective chart review.

Observational
Time Perspective: Retrospective
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Non-Probability Sample

Patients in the congenital surgery database

  • Patients who have undergone repair of ventricular septal defects
  • Patients who have undergone repair of atrioventricular canal defects
  • Ventricular Septal Defects
  • Persistent Common Atrioventricular Canal
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
200
August 2007
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Inclusion Criteria:

  • Patients in the congenital surgery database
  • Patients who have undergone repair of ventricular septal defects
  • Patients who have undergone repair of atrioventricular canal defects
Both
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No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00229827
05-092
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Children's Healthcare of Atlanta
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Principal Investigator: Brian Kogon, MD Emory University
Children's Healthcare of Atlanta
May 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP