Assessing CPR Quality During In-Hospital Cardiac Arrest

This study has been terminated.
Sponsor:
Collaborator:
Laerdal Medical
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT00228293
First received: September 23, 2005
Last updated: September 20, 2013
Last verified: September 2013

September 23, 2005
September 20, 2013
December 2002
Not Provided
  • parameters of CPR quality:
  • chest compression rate
  • chest compression depth
  • ventilation rate
  • ventilation depth
  • CPR pause times
Same as current
Complete list of historical versions of study NCT00228293 on ClinicalTrials.gov Archive Site
  • return of spontaneous circulation (ROSC)
  • survival to hospital discharge
  • 1. return of spontaneous circulation (ROSC)
  • 2. survival to hospital discharge
Not Provided
Not Provided
 
Assessing CPR Quality During In-Hospital Cardiac Arrest
Assessment of Cardiopulmonary Resuscitation Quality During In-Hospital Cardiac Arrest

Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during sequential in-hospital cardiac arrests at the University of Chicago Hospitals. Using an audio feedback system linked to this device, we are studying whether such audio feedback improves CPR quality when provided to rescuers trained in the use of the device.

Patients who suffer cardiac arrest during their hospitalization at the University of Chicago hospitals are given CPR and other resuscitation measures by trained physician and nurse teams. This care is given with the use of defibrillators to monitor cardiac rhythm as well as provide defibrillation as needed.

We have worked closely with engineers at Laerdal Medical Corporation to develop a defibrillator that passively monitors the quality of CPR via additional external sensors (see details in the following reference: Abella BS, Alvarado JP, Myklebust H, Edelson DP, Barry A, O'Hearn N, Vanden Hoek TL, Becker LB. Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA. 2005;293:305-10).

Patients who suffer in-hospital arrest are enrolled (provided they are over 16 years of age, are not pregnant, and are not in the operating room or emergency room setting) with mechanisms to satisfy IRB waiver of consent provisions. These patients receive the same care as before the study, but CPR parameters are recorded by the device. In addition, the device provides audio/visual "coaching" in CPR, based on the actual performance of CPR as measured.

We hypothesize that this coaching will improve CPR quality and hopefully improve survival from cardiac arrest.

The first phase of investigation is now complete, where patients were enrolled and studied without feedback ("baseline" group). Now we are enrolling patients into a second group with feedback provided. Enrollment is nearly complete for this second group. We will then evaluate the baseline and feedback groups to ascertain whether CPR improved over the two cohorts.

Interventional
Phase 2
Phase 3
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Cardiac Arrest
Device: investigational monitor/defibrillator with CPR feedback
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
200
September 2005
Not Provided

Inclusion Criteria:

  • adult patient with cardiac arrest hospitalized at University of Chicago Hospitals

Exclusion Criteria:

  • pregnant
  • arrest in ER or OR
  • pediatric patient
  • patient DNR, no CPR given
  • no CPR given for other reasons (e.g. shock only)
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00228293
IRB11754B, IDE G020121
Not Provided
University of Chicago
University of Chicago
Laerdal Medical
Principal Investigator: Lance B Becker, MD Professor of Medicine, University of Chicago
University of Chicago
September 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP