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Dispatcher-Assisted Resuscitation Trial (DART)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Susan Damon, Public Health - Seattle and King County
ClinicalTrials.gov Identifier:
NCT00219687
First received: September 13, 2005
Last updated: October 28, 2014
Last verified: October 2014

September 13, 2005
October 28, 2014
June 2004
August 2012   (final data collection date for primary outcome measure)
Survival to hospital discharge [ Time Frame: varied ] [ Designated as safety issue: No ]
assessed at hospital discharge
Survival to hospital discharge
Complete list of historical versions of study NCT00219687 on ClinicalTrials.gov Archive Site
Neurological status at hospital discharge [ Time Frame: varied ] [ Designated as safety issue: No ]
assessed at hospital discharge
Neurological status at hospital discharge
Not Provided
Not Provided
 
Dispatcher-Assisted Resuscitation Trial (DART)
Randomized Trial of Dispatcher-Assisted CPR:Chest Compression Alone Versus Chest Compression Plus Ventilation

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.

Out-of-hospital cardiac arrest, a condition characterized by a person suddenly collapsing due to heart stoppage, is a leading cause of death in the United States. In out-of-hospital cardiac arrest, survival is dependent upon what the American Heart Association has termed the chain of survival which includes quick activation of the 9-1-1 system, prompt cardiopulmonary resuscitation (CPR), early defibrillation, and qualified advanced life support care (paramedic care). CPR allows for some circulation and delivery of oxygen to vital organs when the heart is no longer beating on its own. However, in some instances, the citizen bystander has not been trained in CPR, presenting a circumstance where the cardiac arrest victim may not receive CPR until the arrival of emergency medical services (EMS) personnel (i.e., paramedics). The delay in CPR adversely affects outcome and dcreases the chance of survival. In response to this need, the EMS Division of Public Health - Seattle and King County developed and instituted telephone CPR instructions that could be provided "on-the-spot" during a cardiac arrest by the emergency medical (9-1-1) dispatcher. The instructions are designed to be given over the phone to persons who have not had previous CPR training so that they can initiate CPR prior to the arrival of EMS personnel and have been termed "dispatcher-assisted" CPR. The dispatcher instructions provided by the dispatch agencies of King County include the standard "full" CPR protocol of ventilations (breathing into the victim's mouth to inflate the lungs) and chest compressions(pumping on the patients chest to help circulate the blood). The ventilations oxygenate the blood while the chest compressions pump the oxygenated blood forward. This EMS program has led to a considerable increase in the proportion of cardiac arrest victims in King County that receive citizen bystander CPR prior to EMS arrival and has been associated with improved survival (appendix 1).

Comparison: Dispatcher-assisted CPR instructions with compressions and ventillations compared to dispatcher-assisted CPR instructions with compressions only.

Interventional
Phase 3
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Heart Arrest
  • Other: dispatcher-assisted CPR with compressions & ventilations
    Delivery of telephone CPR instructions to lay callers with chest compressions and ventilations when the patient is identified to be in cardiac arrest
  • Other: dispatcher-assisted CPR instructions with compressions only
    Delivery of telephone CPR instructions to lay callers with hands-only chest compressions when the patient is identified to be in cardiac arrest
  • Active Comparator: 1
    When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions only
    Intervention: Other: dispatcher-assisted CPR instructions with compressions only
  • Active Comparator: 2
    When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions and breaths
    Intervention: Other: dispatcher-assisted CPR with compressions & ventilations
Rea TD, Fahrenbruch C, Culley L, Donohoe RT, Hambly C, Innes J, Bloomingdale M, Subido C, Romines S, Eisenberg MS. CPR with chest compression alone or with rescue breathing. N Engl J Med. 2010 Jul 29;363(5):423-33.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
5494
August 2012
August 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance

Exclusion Criteria:

  • Pregnancy
  • Prisoners
  • Cardiac arrest due to asphyxia, drowning, hanging, or electrocution
Both
9 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States,   United Kingdom
 
NCT00219687
RARC-0001-01
Yes
Susan Damon, Public Health - Seattle and King County
Public Health - Seattle and King County
Not Provided
Principal Investigator: Thomas D Rea, MD, MPH Division of Emergency Medical Services, Public Health - Seattle and King County
Principal Investigator: Mickey S Eisenberg, MD, PhD Division of Emergency Medical Services, Public Health - Seattle and King County
Public Health - Seattle and King County
October 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP