Monitoring of Intubation and Ventilation During Resuscitation

This study has been completed.
Sponsor:
Collaborators:
Laerdal Medical
Ullevaal University Hospital
Health Region East, Norway
Norwegian Air Ambulance Foundation
University of Stavanger
Information provided by:
University of Oslo
ClinicalTrials.gov Identifier:
NCT00204217
First received: September 12, 2005
Last updated: August 24, 2007
Last verified: August 2007

September 12, 2005
August 24, 2007
September 2004
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  • sensitivity/specificity for lung ventilation detection
  • correlation ventilation volume - impedance change
Same as current
Complete list of historical versions of study NCT00204217 on ClinicalTrials.gov Archive Site
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Monitoring of Intubation and Ventilation During Resuscitation
Monitoring of Intubation and Ventilation During Resuscitation

Airway control and ventilation is vital during cardiopulmonary resuscitation (CPR) in cardiac arrest. Endotracheal intubation is the gold standard for airway control, but several studies have shown high rates of unrecognized placements of the tube in the esophagus instead of in the airway out-of-hospital. This is lethal. There are no failproof technique for recognising such mistakes clinically in the cardiac arrest situation. Changes on the air volume in the lungs with ventilation changes the impedance (resistance to alternating current) through the thorax. This impedance is already measured routinely by the defibrillators used during CPR. We propose that we can measure ventilation volumes and also discover failed intubations by monitoring this impedance during CPR with the possibility of giving feedback on both to the rescuers.

On the anesthesiologist manned ambulance in Oslo ventilation volumes during CPR will be controlled with a ventilator, the tidal volume varied in random order between 500, 700 and 100 ml, and the volumes be measured continuously as will the impedance between the defibrillator electrodes. In case of failed CPR, the patient will be declared dead. Thereafter the lungs will be ventilated with 700 ml followed by removal of the endotracheal tube, placement of an endotracheal tube in the esophagus and ventilation of this tube, again with monitoring of the impedance.

Interventional
Phase 2
Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Cardiac Arrest
Device: endotracheal intubation
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
15
April 2007
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Inclusion Criteria:

  • Cardiac arrest

Exclusion Criteria:

  • <18 years old trauma pregnancy
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Norway
 
NCT00204217
313-04124
No
Not Provided
University of Oslo
  • Laerdal Medical
  • Ullevaal University Hospital
  • Health Region East, Norway
  • Norwegian Air Ambulance Foundation
  • University of Stavanger
Principal Investigator: Elizabeth Dorph Ulleval University Hospital, University of Oslo
University of Oslo
August 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP