Transcranial Magnetic Treatment (TMS) in Unipolar Depression - Tabular View

Tracking Information

First Received Date ^ICMJE

September 13, 2005

Last Updated Date

September 22, 2009

Start Date ^ICMJE

December 2000

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Hamilton DEpression Rating Scale
Beck Depression Rating Scale

Original Primary Outcome Measures ^ICMJE

Same as current

Change History

Complete list of historical versions of study NCT00186784 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Quantitive Electroencephalographic (QEEG)activity and measures of regional cerebral blood flow

Original Secondary Outcome Measures ^ICMJE

Same as current

Descriptive Information

Brief Title ^ICMJE

Transcranial Magnetic Treatment (TMS) in Unipolar Depression

Official Title ^ICMJE

Repetitive Transcranial Magnetic Stimulation (rTMS) in Unipolar Depression

Brief Summary

Repetitive Transcranial Magnetic Stimulation (rTMS) can improve mood and decrease sadness in patients with depression.

In this study, the investigators seek to increase their understanding about how rTMS improves depression, and to determine which form of rTMS is most effective for depression, when used in combination with antidepressant medication.

Detailed Description

Patients will be assigned for 4 treatment arms, receiving either left high frequency plus right low frequency, or left high frequency plus right sham, or left sham, plus right low frequency, or left sham plus right sham treatment. All subjects will receive treatments for 10 days and will be followed for another 4 weeks.

Study Phase

Phase IV

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Efficacy Study

Condition ^ICMJE

Unipolar Depression

Intervention ^ICMJE

Procedure: Transcranial Magnetic Stimulation (TMS)

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

May 2006

Primary Completion Date

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Major Depression
No physical health problems

Exclusion Criteria:

History of Epilepsy
Metal in the head/neck or skull
Pacemaker
Pregnancy

Gender

Both

Ages

18 Years to 65 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

Canada

Administrative Information

NCT ID ^ICMJE

NCT00186784

Responsible Party

Study ID Numbers ^ICMJE

TMS1871

Study Sponsor ^ICMJE

St. Joseph's Healthcare

Collaborators ^ICMJE

Queen's University, Kingston, Ontario

Investigators ^ICMJE

Principal Investigator:

Gary Hasey, MD

McMaster University

Information Provided By

St. Joseph's Healthcare

Verification Date

September 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP