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Collection of Bone Marrow Aspirate From Volunteer Donors

This study is currently recruiting participants.
Information provided by National Institute on Aging (NIA)

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Descriptive Information Fields
Brief Title  Collection of Bone Marrow Aspirate From Volunteer Donors
Official Title  Collection of Bone Marrow Aspirate From Volunteer Donors for In Vitro Hematopoietic Research
Brief Summary

The purpose of this study is to collect bone marrow cells for research purposes.

Detailed Description

This study is designed to provide bone marrow cells for other research studies. The research is being done because there are ongoing experiments in a number of National Institute on Aging (NIA) laboratories that require access to normal human bone marrow aspirate for their studies of the immune system. These studies are done to understand how blood cells are formed and how they function. Samples will be used to study problems such as the immune system in bone marrow failure and related conditions. Cells will be used in laboratory research and may be banked for future laboratory studies

Study Phase
Study Type  Observational
Study Design  Other, Prospective
Primary Outcome Measure 
Secondary Outcome Measure 
Condition  Aging
Intervention 
MEDLINE PMIDs 11806978,   11698421,   11806973
Links National Institute on Aging This link exits the ClinicalTrials.gov site
Recruitment Information Fields
Recruitment Status  Recruiting
Enrollment  50
Start Date  July 2002
Completion Date December 2012
Eligibility Criteria 

Inclusion Criteria:

  • Healthy volunteers age 18 and over

Exclusion Criteria:

  • Significant abnormalities on health history questionnaire or in the results of blood tests
  • Pregnant or nursing mother
  • Participation in another research study within the past six weeks that is felt by the Principal Investigator to be incompatible with this study
  • Severe infection in the past two months
  • Immune disorder, or use of any medication that can alter immune system function
  • A medical or mental health finding showing inability to go through the procedure
  • Body mass index (BMI) greater than 29%
  • Chronic back pain, sciatica, or a compression fracture of the spine
  • Positive test results for viral infections: Hepatitis B, Hepatitis C, or HIV (AIDS)
Gender Both
Ages 18 Years and older
Accepts Healthy Volunteers Yes
Contacts ††
Contact: Karen Madara, RN     410-350-3929     madarak@grc.nia.nih.gov    
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00183066
Organization ID AG0046
Secondary IDs ††
Study Sponsor  National Institute on Aging (NIA)
Collaborators ††
Investigators 
Principal Investigator:     Dan L. Longo, MD     National Institute on Aging (NIA)    
Information Provided By National Institute on Aging (NIA)
Verification Date August 2008
First Received Date  September 13, 2005
Last Updated Date August 22, 2008

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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