The Influence of Psychological Interventions Upon Disease Progression in HIV-Infected Patients Receiving No Medication

This study has been completed.
Sponsor:
Collaborators:
Hammersmith Hospitals NHS Trust
Johrei Association
Information provided by:
Imperial College London
ClinicalTrials.gov Identifier:
NCT00180700
First received: September 13, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted

September 13, 2005
September 13, 2005
June 2003
Not Provided
CD4 T-cell counts
Same as current
No Changes Posted
  • Other immunological parameters (Viral load levels, NK cell counts)
  • Psychological questionnaires (Perceived Stress Scale (PSS), STAI, Beck depression Inventory (BDI))
  • Endogenous hormone levels (cortisol, DHEA-S and melatonin)
Same as current
Not Provided
Not Provided
 
The Influence of Psychological Interventions Upon Disease Progression in HIV-Infected Patients Receiving No Medication
The Effects of Two Psychological Intervention Techniques, Self-Hypnosis and Johrei Healing Method, on Quality of Life, Psychological Well-Being, EEG Measures and Various Immunological Measures Including CD4+ Counts in Early HIV: a Randomly Controlled Pilot Study

This study examines the hypothesis that psychological interventions have beneficial effects on quality of life including psychological well-being and disease progression in early HIV patients recieving no medication.

Hypothesis: This investigation is based upon the hypothesis that psychological intervention may counteract the detrimental effects of stress both on psychological well-being and on general health.

Background: HIV infection may be considered to be a life-long biological and psychological stressor leading to detrimental outcomes associated with disease progression. Stress reduction in these patients may have beneficial effects through delaying disease progression via the proposed interactive psycho-neuro-endocrine-immune network.

Inclusion Criteria:

HIV infected individuals CD4 T-cell counts above 200 cells/mcl Receiving no anti-retroviral drugs Individuals who signed the informed consent form

Investigative approach: Self-hypnosis and a Japanese non-touching, laying-on-of hands-like technique, called Johrei, were used to investigate the effects of psychological intervention upon immune parameters (especially in CD4 counts) associated with disease progression along with phenomenological associations between stress perception and stress hormone levels in HIV-infected patients receiving no medication.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Educational/Counseling/Training
HIV Infected Individuals
  • Behavioral: Self-hypnosis
  • Behavioral: Johrei - a Japanese stress management system
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
100
December 2004
Not Provided

Inclusion Criteria:

  • HIV infected
  • CD4 T-cell counts above 200 cells/mcl
  • Signed the informed consent form

Exclusion Criteria:

  • receiving anti-retroviral drugs
Both
20 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United Kingdom
 
NCT00180700
Johrei_HIV1
Not Provided
Not Provided
Imperial College London
  • Hammersmith Hospitals NHS Trust
  • Johrei Association
Principal Investigator: John H Gruzelier, Ph.D. Imperial College London
Study Director: Don C Henderson, Ph.D. Imperial College London
Imperial College London
September 2005

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP