Does the Relaxation Response Inhibit Acute Stress?

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2007 by Beth Israel Deaconess Medical Center.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Information provided by:
Beth Israel Deaconess Medical Center
ClinicalTrials.gov Identifier:
NCT00179595
First received: September 13, 2005
Last updated: October 30, 2007
Last verified: October 2007

September 13, 2005
October 30, 2007
May 2002
Not Provided
To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
Same as current
Complete list of historical versions of study NCT00179595 on ClinicalTrials.gov Archive Site
To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.
Same as current
Not Provided
Not Provided
 
Does the Relaxation Response Inhibit Acute Stress?
Does the Relaxation Response Inhibit Acute Stress?

The purposes of this study are:

  1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
  2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.

The purposes of this study are:

  1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
  2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.

Interventional
Phase 2
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Healthy
Behavioral: relaxation response- meditation
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
140
Not Provided
Not Provided

Inclusion Criteria:

  • healthy individual
  • age:18-49 years
  • able to read and understand English
  • able to attend al study visits
  • access to a telephone (to schedule visits)

Exclusion Criteria:

  • current smoking
  • asthma
  • current use of any prescription or psychoactive medications or supplements
  • either:

    1. no prior experience with RR eliciting techniques
    2. at least 3 years of regular RR elicitation (at least 20 min/day)
  • BMI >30
  • exhaled nitric oxide levels >60 ppb
  • abnormal lab values (Hct <32,creatinine >1.3, glucose >200
  • pregnancy
Both
18 Years to 49 Years
Yes
Contact: Jeffery A Dusek, PhD 617-991-0102 jdusek@bidmc.harvard.edu
United States
 
NCT00179595
2001-P-001747, H75-CCH-123424, H75-CCH-119124
Not Provided
Not Provided
Beth Israel Deaconess Medical Center
Centers for Disease Control and Prevention
Principal Investigator: Herbert Benson, MD Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center
October 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP