Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2007 by Hospices Civils de Lyon.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Hospices Civils de Lyon
ClinicalTrials.gov Identifier:
NCT00146926
First received: September 5, 2005
Last updated: April 26, 2007
Last verified: April 2007

September 5, 2005
April 26, 2007
September 2005
Not Provided
After prophylactic solution, evaluation of the pain caused by injection of propofol with a four-point scale before lose of consciousness
Same as current
Complete list of historical versions of study NCT00146926 on ClinicalTrials.gov Archive Site
  • Explicite and implicite memory of pain immediately after surgery and on day one
  • Adverse effects
Same as current
Not Provided
Not Provided
 
Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

Not Provided
Interventional
Phase 3
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Induction of Total Intravenous General Anesthesia
  • Drug: kétamine 20mg
  • Drug: ephedrine 3mg
  • Drug: lidocaine 40mg
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
200
Not Provided
Not Provided

Inclusion Criteria:

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion Criteria:

  • pregnant
  • sedative or analgesic drug 24h before surgery
  • allergy with drug used in the study
  • difficulty of communication
  • absence of informed written consent
Both
18 Years to 75 Years
No
Contact information is only displayed when the study is recruiting subjects
France
 
NCT00146926
2004.367
Not Provided
Not Provided
Hospices Civils de Lyon
Not Provided
Principal Investigator: Vincent PIRIOU, MD Hospices Civils de Lyon
Hospices Civils de Lyon
April 2007

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP