Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema - Tabular View

Tracking Information

First Received Date ^ICMJE

September 2, 2005

Last Updated Date

September 2, 2005

Start Date ^ICMJE

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

length of hospital stay

Original Primary Outcome Measures ^ICMJE

Same as current

Change History

No Changes Posted

Current Secondary Outcome Measures ^ICMJE

radiological changes at follow up

Original Secondary Outcome Measures ^ICMJE

Same as current

Descriptive Information

Brief Title ^ICMJE

Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

Official Title ^ICMJE

Brief Summary

This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.

Detailed Description

Study Phase

Phase I

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Treatment, Randomized, Open Label, Active Control, Parallel Assignment

Condition ^ICMJE

Empyema

Intervention ^ICMJE

Drug: insertion of a chest drain with urokinase instillation
Procedure: primary video-assisted thorascopic surgery

Study Arms / Comparison Groups

Publications *

Jaffe A, Calder AD, Owens CM, Stanojevic S, Sonnappa S. Role of routine computed tomography in paediatric pleural empyema. Thorax. 2008 Oct;63(10):897-902. Epub 2008 May 20.

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

Primary Completion Date

Eligibility Criteria ^ICMJE

Inclusion Criteria:

patients under the age of 16 referred to GOSH for management of empyema

Exclusion Criteria:

Gender

Both

Ages

up to 16 Years

Accepts Healthy Volunteers

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

United Kingdom

Administrative Information

NCT ID ^ICMJE

NCT00144950

Responsible Party

Study ID Numbers ^ICMJE

02AR04

Study Sponsor ^ICMJE

Institute of Child Health

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

Adam Jaffe, Dr

Great Ormond Street Hospital

Information Provided By

Institute of Child Health

Verification Date

September 2005

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP