Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Kathryn Rose, University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier:
NCT00106951
First received: April 1, 2005
Last updated: January 29, 2012
Last verified: January 2012

April 1, 2005
January 29, 2012
April 2005
March 2009   (final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT00106951 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC
Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

To investigate the role of racial and socioeconomic disparities in coronary heart disease (CHD) mortality in the United States.

BACKGROUND:

Despite strong decreases in coronary heart disease (CHD) mortality over past decades, there is evidence that racial and socioeconomic disparities in CHD mortality are increasing. CHD surveillance efforts that examine trends within these population subgroups are an important first step in quantifying and reducing disparities. The Atherosclerosis Risk in Communities (ARIC) Study has monitored rates and trends in validated hospitalized myocardial infarction and fatal CHD among black and white adults aged 35 to 74 years in four U.S. communities since 1989.

DESIGN NARRATIVE:

The study will expand the scope of ARIC surveillance by examining variations in the rates and temporal trends in CHD by socioeconomic status (SES), measured at the level of census tract. For CHD events already included in ARIC surveillance (1992-2002), addresses will be obtained from medical records and death certificates and geocoded so that they can be matched with identifiers for census based geographical areas. The ARIC study will contribute yearly updates of abstracted CHD events and addresses for subsequent years (2003-2005). Each event will be linked with census tract level SES indicators available from the 1990 and 2000 censuses. This novel effort will permit an examination of disparities by SES in rates and trends in fatal CHD, hospitalized myocardial infarction, case fatality, use of invasive cardiac procedures and prescription of efficacious medication at time of hospital discharge. In addition, the extent to which racial disparities in CHD and associated treatments are explained by SES will also be explored.

Observational
Time Perspective: Retrospective
Not Provided
Not Provided
Probability Sample

Community surveillance of adults in four communities in the US

  • Cardiovascular Diseases
  • Coronary Disease
  • Heart Diseases
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
12000
March 2009
March 2009   (final data collection date for primary outcome measure)

hospitalized and fatal coronary heart disease cases eligibility: within 4 defined geographic areas and ages 35 to 74 years of age

Both
35 Years to 74 Years
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00106951
1292, R01HL080287
No
Kathryn Rose, University of North Carolina, Chapel Hill
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Kathryn M Rose, PhD UNC (Adjunct)
University of North Carolina, Chapel Hill
January 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP