The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

This study has been completed.

Sponsor:

Information provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

ClinicalTrials.gov Identifier:

NCT00072917

First received: November 12, 2003

Last updated: January 15, 2010

Last verified: January 2010

History of Changes

Tracking Information
First Received Date ^ICMJE	November 12, 2003
Last Updated Date	January 15, 2010
Start Date ^ICMJE	October 2003
Primary Completion Date	Not Provided
Current Primary Outcome Measures ^ICMJE	Not Provided
Original Primary Outcome Measures ^ICMJE	Not Provided
Change History	Complete list of historical versions of study NCT00072917 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures ^ICMJE	Not Provided
Original Secondary Outcome Measures ^ICMJE	Not Provided
Current Other Outcome Measures ^ICMJE	Not Provided
Original Other Outcome Measures ^ICMJE	Not Provided

Descriptive Information
Brief Title ^ICMJE	The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women
Official Title ^ICMJE	The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women
Brief Summary	This is a longitudinal cohort study of how the responses to a 3 day period of controlled overfeeding relate to subsequent weight gain. We hypothesize that thin individuals are resistant to weight gain because they respond to periods of overfeeding by increasing fat oxidation, reducing food intake, and increasing physical activity relative to those who gain weight over time.
Detailed Description	Not Provided
Study Type ^ICMJE	Observational
Study Design ^ICMJE	Observational Model: Cohort Time Perspective: Prospective
Target Follow-Up Duration	Not Provided
Biospecimen	Retention: Samples With DNA Description: Blood and urine
Sampling Method	Non-Probability Sample
Study Population	Subjects have been recruited through advertisements in local news media and on the internet
Condition ^ICMJE	Obesity Thinness Weight Gain
Intervention ^ICMJE	Not Provided
Study Group/Cohort (s)	Not Provided
Publications *	Not Provided
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.

Recruitment Information
Recruitment Status ^ICMJE	Completed
Estimated Enrollment ^ICMJE	100
Completion Date	June 2008
Primary Completion Date	Not Provided
Eligibility Criteria ^ICMJE	Half of the subjects will be women, half will be men, age 25-35, a range of BMI's from 19-27, for the 'thin subjects' there should be no 1st degree relatives with a BMI>30. Subjects should not engage in planned physical activity more than 3 hrs per week. For the obesity prone group there should be at least 1 1st degree relative with a BMI>30.
Gender	Both
Ages	25 Years to 35 Years
Accepts Healthy Volunteers	Yes
Contacts ^ICMJE	Contact information is only displayed when the study is recruiting subjects
Location Countries ^ICMJE	United States

Administrative Information
NCT Number ^ICMJE	NCT00072917
Other Study ID Numbers ^ICMJE	OVOPOB DK62874 (complted), DK62874
Has Data Monitoring Committee	Yes
Responsible Party	Daniel H. Bessesen, MD, University of Colorado School of Medicine
Study Sponsor ^ICMJE	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborators ^ICMJE	Not Provided
Investigators ^ICMJE	Not Provided
Information Provided By	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Verification Date	January 2010
^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP

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