Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

This study has been completed.
Sponsor:
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
ClinicalTrials.gov Identifier:
NCT00043992
First received: August 16, 2002
Last updated: September 1, 2006
Last verified: September 2006

August 16, 2002
September 1, 2006
July 2001
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Complete list of historical versions of study NCT00043992 on ClinicalTrials.gov Archive Site
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Outdoor Allergen Exposure, Sensitivity, and Acute Asthma
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To examine the role of outdoor pollen grains and fungal spores in the exacerbation of asthma and to produce forecasting models to predict days of high concentration.

Asthma is a growing problem, and outdoor allergens play a role in exacerbation of many cases. A clearer understanding of this role and its magnitude, and a means of controlling the effects of outdoor allergen exposures is needed. We propose Poisson time-series and conditional panel studies to test these hypotheses: 1) The incidence of acute asthma attacks, as measured by urgent care inhalation treatments and hospitalizations for asthma, has a dose-dependent relationship with exposure to specific outdoor allergens; 2) Specific sensitization to outdoor allergens is a risk factor for having an acute attack; and 3) Exposure conditions that lead to acute asthma attacks can be forecast, creating an opportunity to reduce asthma morbidity and mortality ny targeting pretreatment and/or exposure controls.

Observational
Observational Model: Defined Population
Time Perspective: Longitudinal
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Asthma
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1000
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Must be a member of the Fallon HMO and be treated for acute asthma exacerbation.

Both
15 Years to 50 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00043992
9744-CP-001
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National Institute of Environmental Health Sciences (NIEHS)
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National Institute of Environmental Health Sciences (NIEHS)
September 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP