Phase 2 Study of TLK286 Administered Weekly in Advanced Non-Small Cell Lung Cancer - Tabular View

Tracking Information
First Received Date ^ICMJE	July 2, 2002
Last Updated Date	January 10, 2008
Start Date ^ICMJE
Primary Completion Date
Current Primary Outcome Measures ^ICMJE
Original Primary Outcome Measures ^ICMJE
Change History	Complete list of historical versions of study NCT00040638 on ClinicalTrials.gov Archive Site
Current Secondary Outcome Measures ^ICMJE
Original Secondary Outcome Measures ^ICMJE

Descriptive Information
Brief Title ^ICMJE	Phase 2 Study of TLK286 Administered Weekly in Advanced Non-Small Cell Lung Cancer
Official Title ^ICMJE
Brief Summary	The purpose of this study is to determine the effectiveness of TLK286 in the treatment of advanced non-small cell lung cancer.
Detailed Description
Study Phase	Phase II
Study Type ^ICMJE	Interventional
Study Design ^ICMJE	Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Condition ^ICMJE	Carcinoma, Non-Small-Cell Lung
Intervention ^ICMJE	Drug: TLK286
Study Arms / Comparison Groups
Publications *
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information
Recruitment Status ^ICMJE	Completed
Enrollment ^ICMJE	40
Completion Date
Primary Completion Date
Eligibility Criteria ^ICMJE	Inclusion Criteria: Histologic or cytologic diagnosis of non-small cell lung carcinoma Progressed while on or after treatment on platinum-based regimen Patients may not have had more than one prior cytotoxic chemotherapy regimen Stage IV or IIIB Age at least 18 years Adequate liver and kidney function Adequate bone marrow function Exclusion Criteria: Pregnancy or lactation Unstable medical conditions Chemotherapy, hormonal therapy, radiotherapy, radiopharmaceuticals or immunotherapy within 3 weeks of TLK286 CNS metastasis unless controlled by treatment
Gender	Both
Ages	18 Years and older
Accepts Healthy Volunteers	No
Contacts ^ICMJE	Contact information is only displayed when the study is recruiting subjects
Location Countries ^ICMJE	United States

Administrative Information
NCT ID ^ICMJE	NCT00040638
Responsible Party
Study ID Numbers ^ICMJE	TLK286.2014
Study Sponsor ^ICMJE	Telik
Collaborators ^ICMJE
Investigators ^ICMJE
Information Provided By	Telik
Verification Date	February 2007
^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP