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Exposure of Children With Asthma to Household Environmental Tobacco Smoke
This study has been completed.
Study NCT00035685   Information provided by National Heart, Lung, and Blood Institute (NHLBI)
First Received: May 4, 2002   Last Updated: January 18, 2008   History of Changes

May 4, 2002
January 18, 2008
December 2001
 
 
 
Complete list of historical versions of study NCT00035685 on ClinicalTrials.gov Archive Site
 
 
 
Exposure of Children With Asthma to Household Environmental Tobacco Smoke
 

To examine whether or not primary school-aged children with asthma from low-income households have lower household environmental tobacco smoke (ETS) exposure than matched control children.

BACKGROUND:

Children with asthma are particularly vulnerable to environmental tobacco smoke (ETS). However, despite this special vulnerability to ETS, children with asthma are at least as likely to live in smoking households, as are healthy children. Controversy exists, however, about whether or not the smoking members of households with children with asthma use specific strategies to reduce the harmful effects of their smoking on their children more than the smoking members of households of healthy children.

DESIGN NARRATIVE:

The case-control study examines whether or not primary school-aged children with asthma from low-income households have lower household ETS exposure than matched control children. Household ETS exposure will be measured by both objective monitoring, specifically passive nicotine dosimeters and child cotinine assays (the primary hypothesis), and maternal-report (the secondary hypothesis). Ninety children with physician diagnosed asthma and smoking mothers will be matched by age, gender, race/ethnicity, and other relevant variables to 90 healthy children. All children will be recruited from Metro Denver clinics providing services to low-income, underserved populations. The sample will contain equal numbers of African Americans, Hispanics, and Whites. Recruitment will target low-income populations due to their increased prevalence of, and associated morbidity from both asthma and tobacco smoking. Specific household smoking behaviors, as reported by mothers, will be examined for association with household nicotine and child cotinine levels. Finally, a set of carefully chosen measures will be examined in tertiary, exploratory analyses to help understand, clarify, and contextualize the observed results.

N/A
Observational
 
  • Asthma
  • Lung Diseases
 
 
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Completed
 
November 2006
 

No eligibility criteria

Both
6 Years to 12 Years
No
Contact information is only displayed when the study is recruiting subjects
 
 
NCT00035685
 
998
National Heart, Lung, and Blood Institute (NHLBI)
 
Investigator: Frederick Walboldt National Jewish Medical & Research Center
National Heart, Lung, and Blood Institute (NHLBI)
January 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP