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Biological Aspects of Depression and Antidepressant Drugs

This study has been completed.
Study NCT00018733.   Last updated on June 23, 2005.   Information provided by Department of Veterans Affairs

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Descriptive Information Fields
Brief Title  Biological Aspects of Depression and Antidepressant Drugs
Official Title  Biological Aspects of Depression and Antidepressant Drugs
Brief Summary

This study will be measuring changes in depressive symptoms over a 7 week time period. Double-blind placebo controlled trial using the pharmacologic agents Paroxetine or Desipramine.

Detailed Description
Study Phase
Study Type  Interventional
Study Design  Treatment, Randomized, Double-Blind, Placebo Control, Pharmacodynamics Study
Primary Outcome Measure 
Secondary Outcome Measure 
Condition  Depression
Intervention  Drug: paroxetine
Drug: Desipramine
MEDLINE PMIDs
Links
Recruitment Information Fields
Recruitment Status  Completed
Enrollment 
Start Date  September 1996
Completion Date December 2001
Eligibility Criteria 
  • Diagnosis of major depressive disorder Ham-D Score > 18
  • English speaking with ability to read and sign an informed consent
Gender Both
Ages 21 Years to 69 Years
Accepts Healthy Volunteers Yes
Contacts ††
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00018733
Organization ID MHBS-031-99F
Secondary IDs ††
Study Sponsor  Department of Veterans Affairs
Collaborators ††
Investigators 
Investigator:     Steve Brannan, M.D.        
Investigator:     Cheryl Gonzalez, M.D.        
Information Provided By Department of Veterans Affairs
Verification Date December 2004
First Received Date  July 3, 2001
Last Updated Date June 23, 2005

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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