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Comparison of Daily Nocturnal Hemodialysis With Daily Hemodialysis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2003 by National Center for Research Resources (NCRR).
Recruitment status was  Recruiting
Sponsor:
Information provided by:
National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:
NCT00012441
First received: March 6, 2001
Last updated: June 23, 2005
Last verified: December 2003

March 6, 2001
June 23, 2005
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Complete list of historical versions of study NCT00012441 on ClinicalTrials.gov Archive Site
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Comparison of Daily Nocturnal Hemodialysis With Daily Hemodialysis
Comparison of Daily Nocturnal Hemodialysis With Daily Hemodialysis

Hemodialysis remains associated with a high mortality (approximately 22% per year) and many complications despite improvements over the last twenty years. Several nephrologists have suggested that increasing the frequency and amount of dialysis will result in improved outcomes. In fact, various forms of daily dialysis have been performed in over 300 patients in the last 30 years with improvements in blood pressure, quality-of-life, bone disease, and other complications of renal failure. Whether this form of treatment can be expanded to the 220,000 Americans on hemodialysis is unknown. The primary outcome of this study is to determine the effectiveness of nocturnal dialysis in hemodialysis patients in St. Louis. If the pilot study is effective, then participation in a larger, multicenter trial is expected. The endpoints measured are use of antihypertensive medications, improvement in secondary hyperparathyroidism and use of phosphorus binders, quality-of-life measured by SF-36 surveys, and improvement in physical function as measured by maximal oxygen uptake.

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Interventional
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Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Primary Purpose: Treatment
Kidney Failure, Chronic
Procedure: hemodialysis
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
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Adult patients with chronic renal failure requiring intermittent hemodialysis with a life expectancy of greater than 2 years

Both
21 Years to 75 Years
No
United States
 
NCT00012441
NCRR-M01RR00036-0781
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National Center for Research Resources (NCRR)
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National Center for Research Resources (NCRR)
December 2003

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP