Genetic Linkage Study for Hereditary Pancreatitis - Tabular View

Tracking Information

First Received Date ^ICMJE

October 18, 1999

Last Updated Date

September 5, 2006

Start Date ^ICMJE

December 1998

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Original Primary Outcome Measures ^ICMJE

Change History

Complete list of historical versions of study NCT00004475 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Genetic Linkage Study for Hereditary Pancreatitis

Official Title ^ICMJE

Brief Summary

OBJECTIVES:

I. Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene.

Detailed Description

PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients and family members. DNA is extracted from the blood and used for genotypic analysis and linkage analysis.

Patients do not necessarily receive the results of the genetic testing and the results do not influence the type or duration of treatment.

Study Phase

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Natural History

Condition ^ICMJE

Pancreatitis

Intervention ^ICMJE

Procedure: genetic testing

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Recruiting

Enrollment ^ICMJE

Completion Date

Primary Completion Date

Eligibility Criteria ^ICMJE

Diagnosis of hereditary pancreatitis with confirmation of phenotype by: Onset of pain before age 20 Amylase elevation at least 2 times normal Surgical or postmortem confirmation of pancreatitis Unequivocal evidence of pancreatic exocrine insufficiency in the absence of trauma, alcohol abuse, elevated serum lipids, or other known causes
Family member of a patient diagnosed with hereditary pancreatitis

Gender

Both

Ages

Accepts Healthy Volunteers

Contacts ^ICMJE

Location Countries ^ICMJE

United States

Administrative Information

NCT ID ^ICMJE

NCT00004475

Responsible Party

Study ID Numbers ^ICMJE

199/14042, UPMC-951061, UPMC-R01DK54709-01, UPMC-R03DK51954

Study Sponsor ^ICMJE

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborators ^ICMJE

University of Pittsburgh

Investigators ^ICMJE

Study Chair:

David C. Whitcomb

University of Pittsburgh

Information Provided By

Office of Rare Diseases (ORD)

Verification Date

September 2006

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP