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| Descriptive Information Fields | |||||||||
| Brief Title † | Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy | ||||||||
| Official Title † | Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy | ||||||||
| Brief Summary | Magnetic resonance imaging (MRI) and spectroscopy are diagnostic tools that create high quality images of the human body without the use of X-ray (radiation). MRI uses different levels of magnetic fields to create images of the body and organs. Occasionally, researchers will give patients undergoing a MRI an injection of a contrast substance. The contrast substance works by brightening areas of the magnetic resonance image. In this study researchers plan to use magnetic resonance imaging with contrast substances and exercise on normal volunteers in order to evaluate different aspects of its performance. Information gathered from this study may be used to develop more specific research studies involving MRI.... |
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| Detailed Description | Technical evaluation of magnetic resonance imaging and spectroscopy will be performed on normal volunteers. These studies will be conducted in the NIH MRI systems located in Suburban Hospital in Bethesda, Maryland. These studies may involve the intravenous administration of commercially available MR contrast media and exercise. The results will be used to evaluate the performance of various pulse sequences, gradient coils, and RF coils on human subjects and will provide essential ground work for specific patient protocols. |
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| Study Phase | |||||||||
| Study Type † | Observational | ||||||||
| Study Design † | |||||||||
| Primary Outcome Measure † | |||||||||
| Secondary Outcome Measure † | |||||||||
| Condition † | Cardiovascular Disease Healthy |
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| Intervention † | |||||||||
| MEDLINE PMIDs | 7928216, 7862963, 1889423 | ||||||||
| Links | NIH Clinical Center Detailed Web Page  |
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| Recruitment Information Fields | |||||||||
| Recruitment Status † | Recruiting | ||||||||
| Enrollment † | 400 | ||||||||
| Start Date † | February 1999 | ||||||||
| Completion Date | |||||||||
| Eligibility Criteria † |
Any normal volunteer above the age 18 who is capable of giving informed consent will be included. EXCLUSION CRITERIA: A subject will be excluded if he/she has a contradiction to MR scanning.
EXCLUSION CRITERIA FOR GADOLINIUM ENHANCED STUDIES:
Subjects will be excluded if it is deemed that they have a condition that would preclude their use for technical development (e.g. paralyzed hemidiaphragm, morbid obesity, claustrophobia etc.) or present unnecessary risk (e.g. pregnancy, surgery of uncertain type, etc.). Lactating women and subjects with hemoglobinopathies, asthma, or renal or hepatic disease will be excluded from studies involving the adminstration of contrast agents. |
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| Gender | Both | ||||||||
| Ages | 18 Years and older | ||||||||
| Accepts Healthy Volunteers | Yes | ||||||||
| Contacts †† |
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| Location Countries † | United States | ||||||||
| Administrative Information Fields | |||||||||
| NCT ID † | NCT00001874 | ||||||||
| Organization ID | 990048 | ||||||||
| Secondary IDs †† | 99-H-0048 | ||||||||
| Study Sponsor † | National Heart, Lung, and Blood Institute (NHLBI) | ||||||||
| Collaborators †† | |||||||||
| Investigators † | |||||||||
| Information Provided By | National Institutes of Health Clinical Center (CC) | ||||||||
| Verification Date | September 2008 | ||||||||
| First Received Date † | November 3, 1999 | ||||||||
| Last Updated Date | October 21, 2008 | ||||||||
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