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Areas of Brain Responsible for Understanding American Sign Language
This study has been completed.
Study NCT00001782   Information provided by National Institutes of Health Clinical Center (CC)
First Received: November 3, 1999   Last Updated: March 3, 2008   History of Changes

November 3, 1999
March 3, 2008
March 1998
 
 
 
Complete list of historical versions of study NCT00001782 on ClinicalTrials.gov Archive Site
 
 
 
Areas of Brain Responsible for Understanding American Sign Language
Hemispheric Lateralization of Language Receptive Function in the Deaf and in Hearing Individuals Who Learned ASL as First Language

The human brain is made up of two halves called hemispheres. Each half of the brain is responsible for processing different kinds of information. Previous neuroimaging studies have shown that both the right and left hemispheres are involved when processing information given in American Sign Language (ASL). However, the study also showed that when processing spoken language, the left hemisphere was mostly involved.

Researchers would like to find out more about how the brain processes American Sign Language (ASL). This study is designed to determine if the right hemisphere is necessary for normal understanding of ASL.

The purpose of this protocol is to determine if the right hemisphere activation associated with perception of American Sign Language (ASL) in deaf subjects and in normal hearing individuals raised by deaf parents (who learned ASL before written English) is necessary for appropriate understanding of ASL.

 
Observational
 
  • Brain Mapping
  • Deafness
  • Healthy
 
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Completed
30
December 2000
 

Subject age between 18 and 65 years.

Adult hearing offsprings of deaf parents.

Congenitally deaf individuals.

Intact hearing volunteers.

No subjects with personal or family history of seizures or other neurological or demyelinating disorders.

No pregnant women tested after urine pregnancy test.

No subjects with severe coronary disease.

No subjects with metal in the cranium except mouth.

No subjects with intracardiac lines and implanted medication pumps.

No subjects with increased intracranial pressure as evaluated by clinical means.

No subjects with cardiac pacemakers.

No subjects with an intake of neuroleptics.

Both
 
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00001782
 
980082, 98-N-0082
National Institute of Neurological Disorders and Stroke (NINDS)
 
 
National Institutes of Health Clinical Center (CC)
November 1999

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP